Introduction About CHYMODIN FORTE TABLET

CHYMODIN FORTE TABLET contains Trypsin-Chymotrypsin which belongs to the group of medicines called Proteolytic enzymes. It is used to manage post-operative wounds, necrotic tissue, oedema and haematomas like auricular septal hematoma, nasal fractures, parapharyngeal abscess, management of inflammation of the surgical stitches, pelvic inflammatory disease, caesarean section, episiotomy, hysterectomy, tooth extraction, peri-apical abscess, ocular trauma include fluid build-up in the macula (macular oedema), hyphema (collection of blood in eye), black eye, inflammation of uveal tract (uveitis), broken blood vessels (subconjunctival haemorrhage), degenerative joint disorders like rheumatoid arthritis, osteoarthritis, spondylosis, spondylarthritis, pain management, maxillofacial surgery, post-traumatic oedema, soft tissue injury, fractures and dislocation, sports injuries, muscle and joint pain with swelling, sciatica, and sprains and strains.

It is also used to manage chronic respiratory diseases like asthma, bronchitis, lung diseases, and sinus infections. Avoid consumption of alcohol while taking CHYMODIN FORTE TABLET as it may lead to unwanted effects. CHYMODIN FORTE TABLET is not recommended for use in patients with peptic ulcer, glaucoma, blood clotting disorder, severe liver or kidney disease. CHYMODIN FORTE TABLET should be used with caution in patients with lung diseases, and arrhythmias.

CHYMODIN FORTE TABLET is not recommended for use during pregnancy unless considered necessary. CHYMODIN FORTE TABLET is not recommended for use in breastfeeding women. CHYMODIN FORTE TABLET should be used with caution in children. CHYMODIN FORTE TABLET should be used with caution in elderly patients aged 65 years or above. The most common side effects of taking CHYMODIN FORTE TABLET are nausea, vomiting, abdominal pain, bloating, allergy. Contact your physician if any of the symptoms worsen.

Uses Of CHYMODIN FORTE TABLET

It is used to manage:

• post-operative wounds
• necrotic tissue
• oedema
• haematoma like auricular septal hematoma
• nasal fractures, parapharyngeal abscess
• inflammation of the surgical stitches
• pelvic inflammatory disease
• episiotomy, hysterectomy
• tooth extraction
• peri-apical abscess
• ocular trauma includes fluid build-up in the macula (macular oedema), hyphema (collection of blood in the eye), black eye, inflammation of uveal tract (uveitis), broken blood vessels (subconjunctival haemorrhage)
• degenerative joint disorders like rheumatoid arthritis, osteoarthritis, spondylosis, spondyloarthritis
• pain management
• maxillofacial surgery
• post-traumatic oedema
• soft tissue injury, fractures and dislocation, sports injuries, muscle and joint pain with swelling
• sciatica, sprains and strains
• chronic respiratory diseases like asthma, bronchitis, lung diseases, and sinus infections

How CHYMODIN FORTE TABLET Works

CHYMODIN FORTE TABLET works by breaking down the proteins and helps to fight infection and hasten the repair of traumatic, surgical or orthopaedic injuries. It also breaks down the blood clots thus improving and restoring circulation and resolves oedema, hematoma and pain, promotes the removal of the debris and accelerates recovery. It also reduces swelling (oedema), and inflammation, by reducing the proinflammatory mediators and fastens the healing process.

How to use CHYMODIN FORTE TABLET

Take CHYMODIN FORTE TABLET as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine. Your physician will decide the correct dose and duration for you depending on your age, body weight and disease condition.

Side Effects Of CHYMODIN FORTE TABLET

How To Manage Side Effects

Nausea And Vomiting

Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. Contact your doctor if nausea and vomiting do not improve.

Skin rash Or Itching

Avoid a hot water bath as it irritates the skin and does not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if the rashes worsen.

Stomach Pain

Try to rest and relax. Eat small meals but take them frequently. Keep a heating pad on your stomach. Contact your doctor if stomach pain worsens.

Warning & Precautions

Pregnancy

Monitoring required

CHYMODIN FORTE TABLET is not recommended for use during pregnancy unless considered necessary. Contact your doctor before taking it.

Breastfeeding

Contraindicated

CHYMODIN FORTE TABLET is not recommended for use in breastfeeding women. Contact your doctor before taking it.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you experience drowsiness, dizziness, hypotension or a headache after taking CHYMODIN FORTE TABLET.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking CHYMODIN FORTE TABLET as it may lead to unwanted effects.

Kidney

Contraindicated

CHYMODIN FORTE TABLET is not recommended for use in patients with kidney disease. Contact your doctor before taking it.

Liver

Contraindicated

CHYMODIN FORTE TABLET is not recommended for use in patients with severe liver disease. Contact your doctor before taking it.

Allergy

Contraindicated

Do not take CHYMODIN FORTE TABLET if you are allergic to Chymotrypsin-Trypsin, or to other ingredients of this medicine.

Lungs

Use with Caution

CHYMODIN FORTE TABLET should be used with caution in patients with lung diseases. Contact your doctor before taking it.

Heart Disease

Use with Caution

CHYMODIN FORTE TABLET should be used with caution in patients with heart diseases such as arrhythmias. Contact your doctor before taking it.

Use In Pediatrics

Use with Caution

CHYMODIN FORTE TABLET should be used with caution in children. Contact your doctor before taking it.

Use In Geriatrics

Use with Caution

CHYMODIN FORTE TABLET should be used with caution in elderly patients aged 65 years or above. Contact your doctor before taking it.

Interactions

A. Drug-Drug interactions:

Before taking CHYMODIN FORTE TABLET, inform your doctor if you are taking any of the following medicine:

• chloramphenicol (medicines used for bacterial infections)
• coumadin, heparin (medicines used to manage blood clots)
• clopidogrel (medicines used to manage aggregation)
• antiseptics (medicines used to manage infections)

Overdosage:

If you or anyone else accidentally takes too much of CHYMODIN FORTE TABLET, consult your doctor immediately or visit the nearby hospital.

Synopsis

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References

1. Bethesda (MD). Trypsin. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/78383895

2. Dilip Shah, Kushal Mital. mechanism of Chymotrypsin- Trypsin. National Institute of Health. NLM. National Centre for Biotechnology Information. Pubmed.gov. December. 2017. [Accessed on 2nd July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778189

3. MVC Pharmaceuticals. Chymotrypsin- Trypsin. [Revised in September 2017] [Accessed on 2nd July 2022] https://fdaghana.gov.gh/img/smpc/Mimoral%20Enteric%20Coated%20Tablets%20(Trypsin-Chymotrypsin).pdf

4. Chymotrypsin- Trypsin. Cipla Ltd. [Revised in November 2013] [Accessed on 2nd July 2022] https://www.ciplamed.com/content/chymocip-tablets

5. Torrent Pharmaceuticals Ltd. Chymotrypsin- Trypsin. [Revised in August 2015] [Accessed on 2nd July 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2621.pdf