Cellcept 500 Tablet 10's
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Introduction About CELLCEPT 500 TABLET
CELLCEPT 500 TABLET is an immune suppressing agent used to hinder your body rejecting a transplanted organs (such as kidney transplant, heart transplant or liver transplant). It is mostly used in combination with other immune suppressing agents like ciclosporin and steroids.
It contains a medicine called Mycohenolate mofetil which works by suppressing your immune cells that is triggered during auto-immune conditions or organ transplantation.
Avoid excessive sun exposure while taking Cellcept by wearing protective clothings that covers your head, neck, arms and legs and use a sunscreen with high SPF. You must not donate blood during therapy with Cellcept and for at least 6 weeks after stopping the medicine. Men must not donate semen while taking CellCept and for at least 90 days after stopping the medicine.
Cellcept is not recommended for use in pregnant and breastfeeding women due to risk of side effects. Men and women of childbearing potential must use an effective contraceptive method, to avoid pregnancy during the therapy and for atleast 6 weeks after stopping this medicine.
Talk to your doctor immediately if you experience bloody urine, bloody vomits, shortness of breath or skin rashes after taking this medicine.
Uses Of CELLCEPT 500 TABLET
How CELLCEPT 500 TABLET Works
Cellcept 500 Tablet contains a medicine called Mycophenolate mofetil which is an immune suppressing agent. It works by suppressing the immune system where it stops certain cells (called T and B lymphocytes) from multiplying, which are responsible for causing immune responses, like rejecting a transplanted organ or attacking the body in autoimmune diseases. By reducing the activity of these cells, it helps hinder organ rejection or manage conditions where the immune system harms the body.
How to use CELLCEPT 500 TABLET
- Follow your doctor’s instructions exactly regarding the dose and timing.
- Swallow the medicine with a glass of water. Do not crush, chew, or break the tablet
- It is usually advised to take Cellcept 1 hour before or 2 hours after a meal for best absorption
- Take the medicine at the same time each day to maintain steady levels in your body
- If a tablet is broken or crushed, avoid direct contact with your skin, as it may cause irritation.
- Attend follow-up appointments for monitoring of your blood counts and organ function.
Always consult your healthcare provider for personalized guidance.
Side Effects Of CELLCEPT 500 TABLET
Common Side effects of Cellcept:
- Low WBC count causing fever
- Decrease in calcium levels of blood
- Abnormal potassium levels in the blood (high or low)
- Raised uric acid levels in the blood
- High or low blood pressure
- Diarrhoea, nausea, stomach pain, inflammation of the lining of the stomach, abdominal bloating, constipation, indigestion, flatulence, vomiting
- joint or muscle pain
- tiredness, shortness of breath and pale skin (decrease in red blood cells)
- unexpected bleeding and bruising (decrease in blood platelets)
- hypomagnesemia (decrease in magnesium levels of blood)
- dizziness, headache
- cough, shortness of breath, respiratory infection
- acne, skin itching, weakness
- swelling of hands, ankles, or feet
Stop taking this medicine and contact your doctor immediately if you experience any of the following side effects:
- Unexplained bleeding or bruising, bloody urine, bloody stools or vomits
- Fever, signs of cold and flu
- acne, cold sores, shingles, skin growth, hair loss, rash, itching
- bloody urine
- depression, anxiety
- persistent cough or become breathlessness
- rashes, swelling of face, lips, tongue or throat causing difficulty breathing
- swelling of glands, development of a new skin growth or enlargement of an existing skin growth, or changes in an existing mole, may lead to development of cancer of the skin or lymph nodes
Warning & Precautions
Pregnancy
ContraindicatedCellcept Tablet is not recommended for use in pregnant women. Therefore, inform your doctor if you are pregnant or planning to become pregnant before taking this medicine.
Women of childbearing potential must use an effective contraception method to avoid becoming pregnant while undergoing therapy with this medicine.
Breastfeeding
ContraindicatedStudies have shown that mycophenolate mofetil can pass through breast milk to the nursing child. Therefore, do not take Cellcept tablet if you are breastfeeding. Check with your doctor if you are planning to breastfeed.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel drowsiness, somnolence, dizziness, tremor, low blood pressure or numb after taking this medicine.
Allergy
ContraindicatedDo not take this medicine if you are allergic to Mycophenolate mofetil.
Use In Pediatrics
Consult your doctorThis medicine is not recommended for use in children under the age of 2, because there is limited information on its safety and effectiveness.
Use In Geriatrics
Use with CautionThis medicine should be used with caution in elderly patients aged 65 years or above, especially if the individual is suffering from certain viral infections, gastrointestinal bleeding and pulmonary oedema.
Others
CELLCEPT 500 TABLET is not recommended for use if you:
- have hereditary enzyme deficiency such as Lesch-Nyhan (neurogenetic disorder) and Kelley-Seegmiller syndrome (partial deficiency of the enzyme hypoxanthine guanine phosphoribosyl transferase)
Before taking this medicine, inform your doctor if you:
- Have a sign of fever, flu or sore throat
- Have any unexpected bruising (skin discoloration from a skin or tissue injury) or bleeding
- Have digestive problems (such as a stomach ulcer)
- have a rare problem with your metabolism called phenylketonuria (hereditary condition that results in an accumulation of the phenylalanine)
- are planning to get live vaccinations
Interactions
A. Drug-Drug interactions:
Before taking this medicine, inform your doctor if you are taking any of the following medicine:
- other immunosuppressants (such as azathioprine, tacrolimus, belatacept, cyclosporine A)
- cholestyramine (medicine used to manage high cholesterol)
- rifampicin (medicines used to manage infections such as TB)
- Antacids and Proton pump inhibitors (such as aluminium hydroxide, magnesium hydroxide, sodium bicarbonate, calcium carbonate, omeprazole, rabeprazole, pantoprazole)
- phosphate binders (used by patients with chronic renal failure) such as ferric citrate, calcium acetate, sevelamer
- antibiotics (such as amoxicillin and clavulanic acid, doxycycline, ciprofloxacin, clindamycin, metronidazole, azithromycin, trimethoprim/sulfamethoxazole, amikacin, cefadroxil, norfloxacin)
- isavuconazole (medicine used to manage fungal infections)
- telmisartan (medicine used to manage high blood pressure)
- activated charcoal (used to manage digestive problems)
- acyclovir or ganciclovir (medicines used to manage viral infections)
- oral contraceptives such as Ex. ethinylestradiol and levonorgestrel
- probenecid (medicines used to manage gout)
- iron salts such as Ex. ferrous sulphate (medicines used to manage iron deficiency)
- Vaccines
Overdosage:
If you or anyone else accidentally takes too much of this medicine, consult your doctor immediately or visit the nearby hospital. Symptoms include nausea, vomiting, diarrhea, and neutropenia.
Synopsis
| Drug | : | Mycophenolate mofetil |
| Pharmacological Category | : | Immunosuppressants |
| Therapeutic Indication | : | Immune Suppression |
| Dosage Forms | : | Tablet, Capsule, Suspension, Oral suspension |
More Information
Graft rejection occurs when the recipient's immune system attacks a transplanted organ or tissue, recognizing it as foreign. This can lead to damage and failure of the transplant. To prevent rejection, patients are typically prescribed immunosuppressive medications, which reduce immune responses and help the body accept the new organ.
FAQs About CELLCEPT 500 TABLET
Q: What is CellCept 500mg used for?
A: CellCept is used to hinder organ rejection after a kidney, heart, or liver transplant.
Q: What diseases does CellCept treat?
A: It is used in the management of conditions like organ transplant rejection and autoimmune diseases such as lupus nephritis, rheumatoid arthritis, and some forms of vasculitis.
Q: Is CellCept a high-risk medication?
A: As, mycophenolate can increase the risk of infections and other complications, regular monitoring by a healthcare provider is essential while taking CellCept.
Q: Is CellCept a steroid?
A: No, CellCept is not a steroid. It is an immunosuppressant.
Q: How long is it safe to take CellCept?
A: CellCept can be taken long-term under a doctor’s supervision. Regular monitoring is essential to manage side effects and potential risks.
Q: Does CellCept improve kidney function?
A: In conditions like lupus nephritis, CellCept can help reduce inflammation and damage, which may improve kidney function over time.
Q: Is CellCept expensive?
A: It can be expensive without insurance, but costs vary based on location, dosage, and insurance coverage. Generic versions may be more affordable.
Q: Can I stop CellCept suddenly?
A: No, stopping CellCept suddenly can lead to serious complications like organ rejection. Always consult your doctor before changing your dose.
Q: What to avoid when taking CellCept?
A: Avoid live vaccines, close contact with people who are sick, and certain foods or medications that can interact with CellCept, like antacids containing magnesium or aluminium.
Q: Does CellCept weaken your immune system?
A: Yes, it suppresses the immune system to avoid organ rejection or reduce autoimmune activity, increasing the risk of infections.
Q: Can CellCept cause hair loss?
A: Hair loss is a possible side effect of CellCept, though it is not very common.
Q: When do CellCept side effects start?
A: Side effects can start within days to weeks after starting treatment, but it varies based on individual response and dosage.
Q: What is the safest immunosuppressant?
A: There is no one "safest" immunosuppressant as it depends on the condition being treated and the individual’s health. CellCept is considered relatively safe when properly monitored, but others like tacrolimus or azathioprine are also commonly used.
Q: Can CellCept affect your eyes?
A: Eye-related side effects like blurry vision or eye pain are rare but possible. Notify your doctor if you experience any eye issues.
Q: Does CellCept raise blood sugar?
A: CellCept itself doesn’t typically raise blood sugar, but it may in combination with other immunosuppressants like steroids.
Q: Can I take vitamin D with CellCept?
A: Yes, vitamin D is generally safe to take with CellCept, but always consult your doctor before starting new supplements to avoid interactions.
References
- KD Tripathi. Immunosuppressant Drugs. Essentials of Medical Pharmacology. Seventh Edition,2013. Page-883.
- Surjushe A, Saple D G. Mycophenolate mofetil. Indian J Dermatol Venereol Leprol 2008;74:180-184. [Accessed on 27th September 2024]. click here
- Mycophenolate Mofetil in the Treatment of Steroid-Dependent or Frequently Relapsing Nephrotic Syndrome in Children: A Meta-Analysis. NCBI. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. 2021. [Accessed on 27th September 2024] click here
- CellCept 500 mg film-coated tablets mycophenolate mofetil. Roche Registration GmbH. [Accessed on 27th September 2024]. click here
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram Click here
Author Details
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
