Introduction About CEFUDIF CV 625 TABLET

CEFUDIF CV 625 TABLET is a combination of Cefuroxime and Clavulanic acid, which belong to the group of medicines called Antibiotics and Beta-lactamase inhibitors, respectively. It manages various types of bacterial infections like pharyngitis and/or tonsillitis, acute bacterial otitis media, acute bacterial maxillary sinusitis, lower respiratory tract infections including pneumonia, acute bacterial exacerbations of chronic bronchitis and secondary bacterial infections of acute bronchitis, skin and skin structure infections, urinary tract infections, bone and joint infections, gonorrhoea (uncomplicated and disseminated gonococcal infections), early Lyme disease (erythema migrans), septicemia, meningitis, and in switch therapy (injectable to oral) after surgery when the patient's condition is improved.

Before taking CEFUDIF CV 625 TABLET, inform your doctor if you have a history of colitis, liver problems, or kidney problems. CEFUDIF CV 625 TABLET should be used with caution in patients who are penicillin sensitive. CEFUDIF CV 625 TABLET should be used with caution in pregnant women and is not recommended for use in breastfeeding women.

CEFUDIF CV 625 TABLET is not recommended for use in children under the age of three months. The most common side effects of taking CEFUDIF CV 625 TABLET are nausea, vomiting, diarrhea, abdominal discomfort, or pain. Ask your doctor for advice if any of these side effects worsen or don’t improve.

Uses Of CEFUDIF CV 625 TABLET

CEFUDIF CV 625 TABLET is used for the management of various bacterial infections such as:

• Pharyngitis and/or tonsillitis
• Acute bacterial otitis media
• Acute bacterial maxillary sinusitis
• Lower respiratory tract infections, including pneumonia
• Acute bacterial exacerbations of chronic bronchitis and secondary bacterial infections of acute bronchitis
• Skin and skin structure infections
• Urinary tract infections
• Bone and joint infections
• Gonorrhoea (uncomplicated and disseminated gonococcal infections)
• Early Lyme disease (erythema migrans)
• Septicemia
• Meningitis
• Switch therapy (injectable to oral) after surgery when the patient’s condition is improved

How CEFUDIF CV 625 TABLET Works

CEFUDIF CV 625 TABLET is a combination of cefuroxime and clavulanic acid. Cefuroxime is an antibiotic that works by managing the formation of a protective coating on the bacteria, which is essential for their survival. Clavulanic acid is a beta-lactamase inhibitor that works by reducing resistance and enhancing the activity of cefuroxime against bacteria.

How to use CEFUDIF CV 625 TABLET

Take CEFUDIF CV 625 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your physician will determine the correct dose and duration of CEFUDIF CV 625 TABLET for you depending on your age, body weight, and disease condition.

Side Effects Of CEFUDIF CV 625 TABLET

How To Manage Side Effects

Diarrhea

Drink a lot of fluids, such as water, squash, or fruit juice, to keep yourself hydrated. Do not take any medication without first consulting your doctor. Consult with your doctor if the symptom doesn’t improve.

Nausea And Vomiting

Take this medicine with meals or just after meals. Stick to simple meals. Avoid eating rich or spicy food. Consult with your doctor if the symptom doesn’t improve. Drink clear or ice-cold drinks; eat light, bland foods; and avoid fried, oily, or sweet foods. Consult with your doctor if the symptom doesn’t improve.

Stomach Pain

Try to rest and relax. Eat and drink slowly, or try to have smaller and more frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your physician.

Warning & Precautions

Pregnancy

Monitoring required

CEFUDIF CV 625 TABLET should be used with caution in pregnant women only if needed, as there are no adequate and well-controlled studies. Consult your doctor before taking it.

Breastfeeding

Contraindicated

CEFUDIF CV 625 TABLET is not recommended for use in breastfeeding women as small traces may pass through the mother’s milk. Consult your doctor before taking it.

Driving and Using Machines

Use with Caution

Dizziness has been reported during management with CEFUDIF CV 625 TABLET and may affect the ability to drive and use machines. Consult your physician before taking CEFUDIF CV 625 TABLET.

Kidney

Use with Caution

CEFUDIF CV 625 TABLET should be taken with caution in patients with kidney problems. Consult your doctor for advice.

Liver

Use with Caution

CEFUDIF CV 625 TABLET should be taken with caution in patients with liver problems. Consult your doctor for advice.

Allergy

Contraindicated

Do not take CEFUDIF CV 625 TABLET if you are allergic to cefuroxime, clavulanate, or any other cephalosporin antibiotic such as cefadroxil or cephalexin, penicillin, or any of the other ingredients of this medicine.

Use In Pediatrics

Contraindicated

CEFUDIF CV 625 TABLET is not recommended for use in children under 3 months of age, as the safety and efficacy of CEFUDIF CV 625 TABLET have not been established in this group. Consult your physician for advice before taking it.

Use In Geriatrics

Use with Caution

CEFUDIF CV 625 TABLET should be taken with caution in elderly patients. Consult your doctor for advice.

Interactions

A. Drug-Drug Interactions:

Inform your physician if you are taking any of the following drugs before taking CEFUDIF CV 625 TABLET:

• Antacids such as sodium bicarbonate and aluminium hydroxide (used to manage stomach problems)
• Probenecid (used to manage gout)
• Oral contraceptives (combined oral estrogen/progesterone)
• Potent diuretics (Ex. chlorothiazide, indapamide)

Overdosage:

If you or anyone else accidentally take too much of CEFUDIF CV 625 TABLET, consult your doctor immediately or visit the nearby hospital. The symptoms of overdosage of CEFUDIF CV 625 TABLET may include cerebral irritation leading to convulsions.

Synopsis

More Information

FAQs About CEFUDIF CV 625 TABLET

Q: What precautions are to be taken if I take too much CEFUDIF CV 625 TABLET?

A: If you or anyone else accidentally takes too much CEFUDIF CV 625 TABLET, consult your doctor immediately or visit the nearby hospital. The symptoms of overdosage of CEFUDIF CV 625 TABLET may include cerebral irritation leading to convulsions.

Q: Is it safe for children to use CEFUDIF CV 625 TABLET?

A: CEFUDIF CV 625 TABLET is not recommended for use in children under 3 months of age, as the safety and efficacy of CEFUDIF CV 625 TABLET have not been established in this group. Consult your physician for advice before taking

Q: Can CEFUDIF CV 625 TABLET be given to pregnant and breastfeeding women?

A: CEFUDIF CV 625 TABLET should be used with caution in pregnant women only if needed, as there are no adequate and well-controlled studies. CEFUDIF CV 625 TABLET is not recommended for use in breastfeeding women as small traces may pass through the mother’s milk. Consult your physician before taking it.

Q: How does CEFUDIF CV 625 TABLET act?

A: CEFUDIF CV 625 TABLET is a combination of cefuroxime and clavulanic acid. Cefuroxime is an antibiotic that works by managing the formation of a protective coating on the bacteria, which is essential for their survival. Clavulanic acid is a beta-lactamase inhibitor that works by reducing resistance and enhancing the activity of cefuroxime against bacteria.

Q: What are the side effects of CEFUDIF CV 625 TABLET?

A: The most common side effects of taking CEFUDIF CV 625 TABLET are nausea, vomiting, diarrhea, abdominal discomfort, or pain. Ask your doctor for advice if any of these side effects worsen or don’t improve.

Q: What is CEFUDIF CV 625 TABLET used for?

A: CEFUDIF CV 625 TABLET is used to manage various types of bacterial infections like pharyngitis and/or tonsillitis, acute bacterial otitis media, acute bacterial maxillary sinusitis, lower respiratory tract infections including pneumonia, acute bacterial exacerbations of chronic bronchitis and secondary bacterial infections of acute bronchitis, skin and skin structure infections, urinary tract infections, bone and joint infections, gonorrhoea (uncomplicated and disseminated gonococcal infections), early Lyme disease (erythema migrans), septicemia, meningitis, and in switch therapy (injectable to oral) after surgery when the patient's condition is improved.

Q: What precautions must be taken while using CEFUDIF CV 625 TABLET?

A: CEFUDIF CV 625 TABLET should be taken with caution in patients with kidney problems, liver problems, sensitivity to penicillin, and colitis. Consult your doctor for advice.

Q: Who should not take CEFUDIF CV 625 TABLET?

A: Do not take CEFUDIF CV 625 TABLET if you are allergic to cefuroxime. Clavulanate any other cephalosporin antibiotic such as cefadroxil or cephalexin, penicillin, or any of the other ingredients of this medicine.

Q: Is CEFUDIF CV 625 TABLET a steroid?

A: No, CEFUDIF CV 625 TABLET is a combination of cefuroxime and clavulanic acid, which belong to the group of medicines called antibiotics and beta-lactamase inhibitors, respectively. It manages various bacterial infections.

Q: Is CEFUDIF CV 625 TABLET safe for kidneys?

A: CEFUDIF CV 625 TABLET should be taken with caution in patients with kidney problems. Consult your doctor for advice.

References

1. KD Tripathi. Beta-Lactam Antibiotics, Antimicrobial Drugs. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 721 & 728.

2. Himanshu Gupta, Reena Gupta, Sumit Rai, Himanshu Kataria. Is empirical use of the antibiotic combination of cefuroxime and clavulanic acid rational? Journal of Global Antimicrobial Resistance. March 2019. [Accessed on 25th July 2024] https://www.researchgate.net/publication/330130875_

3. Dr. Anuradha De, Dr. Ruchi Tayal, and Dr. Sujata Baveja. Comparison of the sensitivity of Cefuroxime- Clavulanic acid combination vs. Cefuroxime alone in biofilm and/or beta-lactamase-producing bacteria. December 2015. [Accessed on 25th July 2024] https://storage.googleapis.com/journal-uploads/ejbps/article_issue/volume_3_january_issue_1/1451545156.pdf

4. Umano Healthcare. Cefuroxime and Clavulanic Acid. [Accessed on 25th July 2024] https://umanohealthcare.com/umoxim-cv/

5. Incepta pharma. Cefuroxime and Clavulanic Acid. [Accessed on 25th July 2024] http://www.inceptapharma.com/product-details.php?pid=510

6. Radiant Pharmaceuticals. Cefuroxime and Clavulanic Acid. [Accessed on 25th July 2024] http://www.radiantpharmabd.com/products/78/details

7. ACI Limited. Cefuroxime and Clavulanic Acid. [Accessed on 25th July 2024] https://www.aci-bd.com/Brand/Cerox%20CV.pdf

8. MK Medicine. Cefuroxime and Clavulanic Acid. [Accessed on 25th July 2024] https://www.mkmedicine.in/cefuroxime-axetil-ip-500-mg-clavulanic-acid-125-mg-tablet.html

9. Wellona Pharma. Cefuroxime and Clavulanic Acid. [Accessed on 25th July 2024] https://wellonapharma.com/product/finished/cefuroxime-and-potassium-clavulanate-tablets

Useful Diagnostic Tests

• Complete Blood Count (CBC)/ Hemogram
• Kidney Function Test (KFT)
• Peripheral Smear Examination By Pathologist
• Serum Electrolytes/ Electrolytes Profile
• Culture & Sensitivity, Blood
• Healthy Midlife Checkup
• Urine Routine & Microscopy
• Women Health Checkup - Essential
• Full Body Checkup – Gold

Author Details

Written By Dr. N. Sai Swaroop - Pharm.D

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 30 Jul 2024 | 03:26 PM(IST)