Introduction About CEFREDROX O TABLET

CEFREDROX O TABLET is a combination of Cefpodoxime and Ofloxacin which belongs to the group of medicines called Antibiotics. CEFREDROX O TABLET is used to manage mild to moderate bacterial infections such as acute otitis media, pharyngitis, and sinusitis.

CEFREDROX O TABLET is not recommended for use in patients allergic to Cefpodoxime, Ofloxacin, and/other cephalosporin antibiotics (such as cephalexin). It is also not recommended for use in patients suffering from epilepsy.

Before taking CEFREDROX O TABLET, inform your doctor if you have stomach/intestinal disease, blood clotting disorders, diarrhoea, kidney disease, and/or liver disease.

CEFREDROX O TABLET is not recommended for use during pregnancy as it may cause harm to the foetus. It is also not recommended for use in breastfeeding women since it may pass through breast milk.

CEFREDROX O TABLET is not recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged above 65 years) after consulting the doctor.

The most common side effects of taking CEFREDROX O TABLET are stomach pain, nausea, vomiting, diarrhea, dizziness, headache, and/or pain in neck, lower legs. Consult your doctor if any of these side effects worsens.

Uses Of CEFREDROX O TABLET

It is used to manage mild to moderate bacterial infections such as:

• acute otitis media (middle ear infection)
• pharyngitis (sore throat)
• sinusitis (infection of sinus)

How CEFREDROX O TABLET Works

CEFREDROX O TABLET manages bacterial infections, where Cefpodoxime works by managing the formation of the bacterial protective covering which is essential for the survival of the bacteria in the human body and Ofloxacin works by inhibiting DNA gyrase (enzyme responsible for replication, transcription and repair of the DNA) which results in destruction of bacteria thus managing and managing the spread of bacterial infection in affected individuals.

How to use CEFREDROX O TABLET

Take CEFREDROX O TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects Of CEFREDROX O TABLET

How To Manage Side Effects

Nausea and Vomiting:

Take CEFREDROX O TABLET with or just after a meal. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Inform your doctor if the condition worsens.

Diarrhoea:

Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult and inform your doctor if the symptom worsens.

Dizziness:

Try to rest and get enough sleep. Try to avoid driving or operating any tools or machines while you feel dizzy. Limit consumption of alcohol, as it can aggravate dizziness. Consult and inform your doctor if the symptom worsens.

Headache:

If CEFREDROX O TABLET causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking CEFREDROX O TABLET. If it lasts more than a week or severe, inform your doctor.

Warning & Precautions

Pregnancy

CEFREDROX O TABLET is not recommended for use during pregnancy since the medicine may harm the foetus. Consult your doctor before taking CEFREDROX O TABLET.

Breastfeeding

CEFREDROX O TABLET is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking the medicine.

Driving and Using Machines

Do not drive or operate any machines if you experience sleepiness, dizziness, and/or blurred vision after taking [GBNEYWORD].

Alcohol

Avoid alcohol consumption of alcohol while taking CEFREDROX O TABLET since it may cause drowsiness.  

Kidney

CEFREDROX O TABLET should be used caution in patients with kidney disease. Consult your doctor before taking CEFREDROX O TABLET.

Liver

CEFREDROX O TABLET should be used with caution in patients with liver disease. Consult your doctor before taking CEFREDROX O TABLET.

Allergy

Do not take CEFREDROX O TABLET if you are allergic to Cefpodoxime, Ofloxacin, other cephalosporin antibiotics (such as cephalexin), and/or any other ingredients of this medicine.

Interactions

A. Drug-Drug interactions:

Inform your doctor about all the medicines you use including prescription, non-prescription and herbal medicines.

B. Drug-Food interaction:

Avoid consuming milk and dairy products as it may alter the effect the medicine. Consult your doctor before taking CEFREDROX O TABLET.

Overdosage:

If you or anyone else accidentally take too much of CEFREDROX O TABLET, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep CEFREDROX O TABLET out of reach of children
• Store CEFREDROX O TABLET at room temperature

FAQs About CEFREDROX O TABLET

What is CEFREDROX O TABLET used for?

CEFREDROX O TABLET is a combination of Cefpodoxime and Ofloxacin which belongs to the group of medicines called Antibiotics. It is generally used to manage mild to moderate bacterial infections such as acute otitis media, pharyngitis, and sinusitis in affected individuals.

What are the side effects of CEFREDROX O TABLET?

The most common side effects of taking CEFREDROX O TABLET are stomach pain, nausea, vomiting, diarrhea, dizziness, headache, and/or pain in neck, lower legs. Consult your doctor if any of these side effects worsens.

How CEFREDROX O TABLET works?

CEFREDROX O TABLET manages bacterial infections, where Cefpodoxime works by managing the formation of the bacterial protective covering which is essential for the survival of the bacteria in the human body and Ofloxacin works by inhibiting DNA gyrase (enzyme responsible for replication, transcription and repair of the DNA) which results in destruction of bacteria thus managing and managing the spread of bacterial infection in affected individuals.

How to take CEFREDROX O TABLET?

Take CEFREDROX O TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Can CEFREDROX O TABLET be used in children?

No, CEFREDROX O TABLET is not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before taking CEFREDROX O TABLET.

References

1. K.D. Tripathi. Beta-lactam Antibiotics and Sulphonamides, Cotrimoxazole & Quinolones. Essentials of medical pharmacology. Seventh edition. 2013. Page- 728, 713.

2. M T Borin, J J Ferry, K K Forbes, G S Hughes. Pharmacokinetics of cefpodoxime proxetil in healthy young and elderly volunteers. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. [Revised in July 1994] [Accessed on 11th June 2022] https://pubmed.ncbi.nlm.nih.gov/7929873/

3. P Veyssier, J B Fourtillan, J Modai, W Couet, M A Lefebvre, J P Darchis, M Vincent Du Laurier, A Bryskier. Pharmacokinetics of ofloxacin in the elderly (65-85 years) with normal renal function after a single oral dose of 200 mg. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. [Revised in June 1986] [Accessed on 11th June 2022] https://pubmed.ncbi.nlm.nih.gov/3534750/

4. Saintroy Lifescience. Olipod-OF 100. [Accessed on 11th June 2022] https://m.saintroylifescience.com/cefpodoxime-and-ofloxacin-tablets-6873585.html

5. Integrated Laboratories Pvt Ltd. INTEDPOD - OF. [Accessed on 11th June 2022] https://integratedlaboratories.in/cefpodoxime-proxetil-ofloxacin-200-mg-tablets-intepod-of/

6. Vibcare Pharma Pvt. Ltd. ODOXICEF O / CEFDOFEC O. [Accessed on 11th June 2022] https://vibcare.co.in/cefpodoxime-ofloxacin/

7. Alpha Drugs. SYFEDOX-O. [Accessed on 11th June 2022] https://www.alphadrug.in/product/syfedox-o/

8. Zeelab Pharmacy. Zedoxy-O 200. [Accessed on 11th June 2022] https://zeelabpharmacy.com/product/zedoxy-o-200

9. Smotec Pharmaceuticals. SMOPOD-OF. [Accessed on 11th June 2022] https://www.smotecpharma.com/smopod-of

10. StayHappi Pharmacy. Cefpodoxime Proxetil & Ofloxacin Tablets. [Accessed on 11th June 2022] https://www.stayhappi.com/stayhappi-generics/cefpodoxime-proxetil-200-mg-ofloxacin-200-mg-tablet-10s-8665

11. Wellona Pharma. CEFPOWELL-OF. [Accessed on 11th June 2022] https://wellonapharma.com/product/finished/cefpodoxime-and-ofloxacin-tablets

12. Actiza Pharmaceutical Private Limited. Cefpodoxime and ofloxacin tablets. [Accessed on 11th June 2022] https://www.actizapharma.com/products/cefpodoxime-proxetil-ofloxacin/

13. Alpic Remedies Ltd. Cipalp-O. [Accessed on 11th June 2022] https://www.alpicremediesltd.com/cefpodoxime-proxetil-200-mg-ofloxacin-3348739.html

Useful Diagnostic Tests

• Complete blood count

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 23 Dec 2022 | 10:49 AM(IST)