Introduction About CAPNEA SOLUTION

CAPNEA SOLUTION contains Caffeine which belongs to the group of medicines called CNS stimulants. It is used to manage primary apnea (episodes of interrupted breathing) in premature babies. Primary apnea in premature babies happens due to immature development of baby’s breathing centers.

CAPNEA SOLUTION has been shown to reduce the number of episodes of interrupted breathing in premature newborns babies. It can also be used to manage bronchopulmonary dysplasia (airway damage) among premature babies.

Before CAPNEA SOLUTION is administered, inform your doctor if you child has any liver, kidney or heart problems. You must also inform your doctor if your child suffers from seizure disorders, slow weight gain or frequent regurgitation (spitting up of milk or food) as a precaution.

If you are the mother of the premature infant who receives the management, you must not drink coffee or take foods which has high caffeine content. This is because the caffeine taken by the breastfeeding mother may pass through the breast milk to the nursing premature infant who is already receiving caffeine therapy and may lead to an overdosage. The most common side effect of CAPNEA SOLUTION is fast or irregular heart rate. Consult your doctor if it worsens.

Uses Of CAPNEA SOLUTION

• Manage primary apnea (episodes of interrupted breathing) in premature babies
• Manage and manages bronchopulmonary dysplasia (airway damage) in premature babies

How CAPNEA SOLUTION Works

CAPNEA SOLUTION is a CNS stimulant. It works by stimulating a part of the brain that controls breathing. As a result, the brain transfers a lot of breathing signals to the lungs which makes the lungs breathe more deeper and faster. It also increases the number of breathing cycles, manages the airway damage and reduces the need for mechanical ventilation.

How to use CAPNEA SOLUTION

CAPNEA SOLUTION will be administered orally (via gastric feeding tube) to your child only by a doctor or a nurse.

Your doctor will decide the correct dose and duration of therapy for your child based on their gestational age, body weight and health condition.

Side Effects Of CAPNEA SOLUTION

Warning & Precautions

Breastfeeding

Contraindicated

If you are the mother of the premature infant who receives the management, you must not drink coffee or take foods which has high caffeine content. This is because the caffeine taken by the breastfeeding mother may pass through the breast milk to the nursing premature infant who is already receiving caffeine therapy and may lead to an overdosage.

Kidney

Use with Caution

CAPNEA SOLUTION should be used with caution in babies with kidney problems. Therefore, inform your doctor as a precaution.

Liver

Use with Caution

CAPNEA SOLUTION should be used with caution in babies with liver problems. Therefore, inform your doctor as a precaution.

Allergy

Contraindicated

If your child is allergic to caffeine, kindly inform your doctor before CAPNEA SOLUTION is administered to the child.

Heart Disease

Use with Caution

CAPNEA SOLUTION should be used with caution in babies with heart problems (such as irregular heart rate). Therefore, inform your doctor as a precaution.

Use In Pediatrics

Safe

CAPNEA SOLUTION can be used in premature infants born between 28-33 gestation weeks (7-8 months of pregnancy) under careful medical supervision.

Interactions

A. Drug-Drug interactions:

Before CAPNEA SOLUTION is administered to the child, kindly inform the doctor if your child is given any of the following medicines as a precaution:

• other medicines that help in breathing (Ex. theophylline, doxapram)
• medicines used to control fits (such as phenobarbitone or phenytoin) taken by the mother during pregnancy before delivering the baby
• ketoconazole (a medicine used to manage fungal infections)
• medicines used to manage stomach ulcers (such as omeprazole, pantoprazole, rabeprazole, ranitidine, famotidine, cimetidine, etc.)

Overdosage:

CAPNEA SOLUTION will be administered only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor if you notice fits or any other side effects in your child.

Synopsis

More Information

• Keep CAPNEA SOLUTION out of reach of children
• Store CAPNEA SOLUTION at room temperature

FAQs About CAPNEA SOLUTION

Q: What is the use of CAPNEA SOLUTION?

A: CAPNEA SOLUTION is used to manage primary apnea (episodes of interrupted breathing) in premature babies. It can also be used to manage bronchopulmonary dysplasia (airway damage) among premature babies.

Q: How CAPNEA SOLUTION helps in breathing problems?

A: CAPNEA SOLUTION is a CNS stimulant. It works by stimulating a part of the brain that controls breathing. As a result, the brain transfers a lot of breathing signals to the lungs which makes the lungs breathe more deeper and faster. It also increases the number of breathing cycles, manages the airway damage and reduces the need for mechanical ventilation.

Q: Is CAPNEA SOLUTION safe for use in children?

A: CAPNEA SOLUTION can be used in premature infants born between 28-33 gestation weeks (7-8 months of pregnancy) under careful medical supervision.

Q: Why newborn babies suffer from apnea?

A: Primary apnea in premature babies happens due to immature development of baby’s breathing centers.

Q:  What are the side effects of CAPNEA SOLUTION?

A: The most common side effect of CAPNEA SOLUTION is fast or irregular heart rate. Consult your doctor if it worsens.

Q: Is CAPNEA SOLUTION effective?

A: CAPNEA SOLUTION effectively improves breathing among infants suffering from apnea of prematurity. It works by stimulating a part of the brain that controls breathing. It also increases the number of breathing cycles, manages the airway damage and reduces the need for mechanical ventilation.

References

1. KD. Tripathi. Drugs for Cough and Bronchial asthma. CNS Stimulants and Cognition Enhancers. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 224, 227& 488.

2. Justin Evans; John R. Richards; Amanda S. Battisti. Caffeine. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2022. [Accessed on 25th March 2023] https://www.ncbi.nlm.nih.gov/books/NBK519490/

3. Macarthys Laboratories Limited. Caffeine Citrate Oral solution. Electronic Medicines Compendium [Revised in July 2018] [Accessed on 25th March 2023] https://www.medicines.org.uk/emc/files/pil.5145.pdf

4. American Regent, Inc. Caffeine Citrate Injection, Solution. Dailymed.com. [Revised in September 2020]. [Accessed on 25th March 2023] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d17e3be5-514f-454a-8347-d804cd5ec37f

5. Central Drugs Standard Control Organization. Caffeine Citrate Oral Solution. July 2009. [Accessed on 25th March 2023] https://cdscoonline.gov.in/CDSCO/Drugs