CABERNORM Tablet 4's
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Introduction About CABERNORM TABLET
CABERNORM TABLET contains cabergoline, which belongs to the group of medicines called dopamine agonists. Dopamine is a chemical produced naturally in the body that helps transmit messages to the brain. Cabergoline works by blocking the release of prolactin hormone in the brain and controlling symptoms associated with hormonal disturbances.
CABERNORM TABLET is not recommended for use in patients with severe liver disease, stiff and inflamed heart valves (cardiac valvulopathy) and uncontrolled high blood pressure. Consult your doctor before taking it.
CABERNORM TABLET should be used with caution in patients with pain in the chest while breathing, fluid in the lungs, inflammation or infection of the lungs, reduced liver function, kidney problems, cardiovascular diseases, low blood pressure. Consult your doctor before taking it.
CABERNORM TABLET is not recommended for use in pregnant women and breast-feeding women. It is also not recommended for use in children under 16 years of age. Consult your doctor before taking it.
The most common side effects after taking CABERNORM TABLET are drowsiness, nausea, headache, dizziness, vertigo, stomach pain, indigestion, inflamed stomach lining, fatigue, lack of bodily strength, weakness. Consult your doctor if any of the symptoms worsen.
Uses Of CABERNORM TABLET
- Blocks the release of prolactin hormone in the brain
How CABERNORM TABLET Works
CABERNORM TABLET works by decreasing the amount of a hormone called prolactin (a hormone that is responsible for milk production and breast tissue development).
How to use CABERNORM TABLET
Take CABERNORM TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
It can be taken with or after food to help reduce feelings of nausea or vomiting. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. You should not stop taking CABERNORM TABLET until your doctor tells you.
Side Effects Of CABERNORM TABLET
Common
- drowsiness, headache
- nausea, vomiting, stomach pain, indigestion, inflamed stomach lining, constipation
- dizziness, vertigo
- fatigue, lack of bodily strength, weakness
- blurred vision
- low blood pressure after childbirth
- breast pain
- depression
- sleep disturbances, excessive daytime drowsiness/sleepiness
- low blood pressure (which can result in dizziness upon standing)
- hot flushes
Uncommon
- loss of hair
- severe itching, rash, hypersensitivity reaction
- fainting, shortness of breath
- nosebleed
- leg cramps, muscle spasm
- oedema
- irregular or strong heartbeat (palpitations)
- crawling, pins and needles sensation
- temporary partial vision loss
- cold hands and feet
- fibrotic reactions (including fibrosis affecting the lungs), fluid in the layers of the membrane lining the lungs and chest cavity (pleural effusion)
Rare
- cramp in fingers
Stop taking CABERNORM TABLET and contact your doctor immediately if you experience any of the following side effects:
- abnormal or unusual thoughts
- heart valve and related disorders Ex. inflammation of heart (pericarditis) or leakage of fluid in the pericardium (pericardial effusion). Symptoms include difficulty breathing, shortness of breath, pounding heart, feeling faint, chest pain, back pain, pelvic pain or swollen legs. These may be the first signs of a condition called pulmonary fibrosis, which can affect the lungs, heart or heart valves or lower back
- allergic reactions such as widespread itchy rash, difficulty breathing with or without wheezing, feeling faint, unexplained swelling of the body or tongue
How To Manage Side Effects
Constipation
Eat plenty of fibre rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly. Contact your doctor if constipation persist.
Diarrhea
Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Do not take any medicine on your own for managing diarrhea. Contact your doctor if the diarrhea did not improve.
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling dizzy. Do not consume alcohol, as it can aggravate your dizziness. Contact your doctor if the dizziness did not improve.
Headache
Rest and relax. Drink plenty of fluids such as water or electrolytes and apply a pain-relieving balm on the head if necessary. Do not consume alcohol. Contact your doctor if the headache did not improve.
Nausea And Vomiting
Take the medicine with or just after a meal. Stick to simple meals. Avoid eating oily or spicy food. Contact your doctor if nausea or vomiting did not improve.
Stomach Pain
Try to have smaller meals but take frequently. Keep a heat pad on your stomach. Do not self-manage and contact your doctor if the stomach pain did not improve.
Warning & Precautions
Pregnancy
ContraindicatedCABERNORM TABLET is not recommended for use in pregnant women and you should also take care not to become pregnant for at least one month once you have stopped taking CABERNORM TABLET.
If you become pregnant during management with CABERNORM TABLET, stop taking this medicine and contact your doctor who will then monitor your pregnancy as CABERNORM TABLET can result in congenital abnormalities if you use it during pregnancy.
Breastfeeding
ContraindicatedCABERNORM TABLET is not recommended for use in breast feeding as this medicine will stop you producing milk for your baby. If you need to take CABERNORM TABLET you should use another method of feeding your baby.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel drowsy, and sudden sleepy after taking CABERNORM TABLET.
Alcohol
Consult your doctorAvoid alcohol consumption while taking CABERNORM TABLET as it increases the risk of dizziness.
Kidney
Use with CautionCABERNORM TABLET should be used with caution in patients with kidney problems. Consult your doctor before taking CABERNORM TABLET.
Liver
Consult your doctorCABERNORM TABLET is not recommended for use in patients with severe liver disease. It should be used with caution in patients with reduced liver function. Contact your doctor before taking CABERNORM TABLET.
Allergy
Use with CautionDo not take CABERNORM TABLET if you are allergic to Cabergoline or to other medicines called ergot alkaloids (Ex. pergolide, bromocriptine, lisuride, ergotamine or ergometrine) or to any of the other ingredients of this medicine (lactose).
Lungs
Use with CautionCABERNORM TABLET should be used with caution in patients with pain in the chest while breathing, fluid in the lungs, inflammation or infection of the lungs. Consult your doctor before taking CABERNORM TABLET.
Heart Disease
Consult your doctorCABERNORM TABLET is not recommended for use in patients with stiff and inflamed heart valves (cardiac valvulopathy) and uncontrolled high blood pressure.
It should be used with caution in patients with cardiovascular diseases (disease that affects the heart and blood vessels), low blood pressure (postural hypotension). Consult your doctor before taking CABERNORM TABLET.
Use In Pediatrics
ContraindicatedCABERNORM TABLET is generally not recommended for use in children under 16 years of age. Consult your doctor before taking it.
Use In Geriatrics
Use with CautionCABERNORM TABLET should be used with caution in elderly patients (above 65 years). Consult your doctor before taking it.
Others
CABERNORM TABLET is not recommended for use if you have:
- history of mental illness associated with childbirth (puerperal psychosis)
- fibrotic reactions (scar tissue) affecting the abdomen, heart or lungs
- swelling of hands and feet and a high blood pressure during pregnancy (preeclampsia, eclampsia)
Before taking CABERNORM TABLET, inform your doctor if you have:
- cold hands and feet (Raynaud’s syndrome)
- peptic ulcer or GI haemorrhage (bleeding from the stomach and intestines)
- history of serious mental disease (psychotic disorders)
- just given birth you may be more at risk of certain conditions like high blood pressure, convulsion, stroke or mental health problems
- increased blood pressure after giving birth
Interactions
A. Drug - Drug interactions:
Before taking CABERNORM TABLET, inform your doctor if you are taking any of the following medicine:
- medicines used to manage mental illness (Ex. chlorpromazine, haloperidol)
- medicines for nausea and vomiting (Ex. domperidone, metoclopramide)
- medicines for Parkinson’s disease (Ex. Levodopa, bromocriptine)
- medicines for severe migraine headaches (Ex. pergolide, bromocriptine, lisuride, methysergide, ergotamine, dihydroergotamine, ergometrine)
- medicines used to manage infections (Ex. erythromycin)
- medicines to lower your blood pressure (Ex. amlodipine, lisinopril, metoprolol)
Overdosage:
If you or anyone else accidentally take too much of CABERNORM TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are nausea, vomiting, gastric complaints, low blood pressure when standing, confusion/psychosis or hallucinations.
Synopsis
| Drug | : | Cabergoline |
| Pharmacological Category | : | Dopamine agonists |
| Therapeutic Indication | : | To stop breast milk production and manages hormonal disturbances |
| Dosage Forms | : | Tablet |
More Information
- Keep CABERNORM TABLET out of the sight and reach of children
- Store CABERNORM TABLET below 30°C
FAQs About CABERNORM TABLET
Q. Who should not take CABERNORM TABLET?
A. CABERNORM TABLET is not recommended for use in patients with severe liver disease, stiff and inflamed heart valves (cardiac valvulopathy) uncontrolled high blood pressure, history of mental illness associated with childbirth, fibrotic reactions (scar tissue) affecting the abdomen, heart or lungs, swelling of hands and feet and a high blood pressure during pregnancy (preeclampsia, eclampsia) and in breastfeeding women. It is also not recommended for use in children under 16 years of age, allergic history to cabergoline or to other medicines called ergot alkaloids (Ex. pergolide, bromocriptine, lisuride, ergotamine or ergometrine). Consult your doctor before taking it.
Q. Does CABERNORM TABLET increase fertility?
A. CABERNORM TABLET is taken as one to two tablets twice each week and helps to restore ovulation and normal prolactin levels. Of the women manageed, approximately 85% will ovulate and can become pregnant if no other causes of infertility are present.
Q. Is CABERNORM TABLET safe to use in patients with liver disease?
A. CABERNORM TABLET should be used with caution in patients with pain in the chest while breathing, fluid in the lungs, inflammation or infection of the lungs. Consult your doctor before taking it.
Q. Is CABERNORM TABLET safe in pregnancy?
A. CABERNORM TABLET is not recommended for use in pregnant women and you should also take care not to become pregnant for at least one month once you have stopped taking this medicine. If you become pregnant during management with CABERNORM TABLET, stop taking this medicine and contact your doctor who will then monitor your pregnancy as CABERNORM TABLET can result in congenital abnormalities if you use it during pregnancy.
Q. What side effects can be expected while using CABERNORM TABLET?
A. The most common side effects after taking CABERNORM TABLET are drowsiness, nausea, headache, dizziness, vertigo, stomach pain, indigestion, inflamed stomach lining, fatigue, lack of bodily strength, weakness. Consult your doctor if any of the symptoms worsen.
Q. Can CABERNORM TABLET be used in children?
A. The safety and effectiveness of CABERNORM TABLET have not been established in children and adolescents (aged below 16 years). Therefore, consult your doctor for advice.
References
1. Laurence L. Brunton, John S. Lazo, Keith L. Parker. Hormones and Hormones antagonist. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 11th edition. 2006. Page – 1500.
2. Tulloch KJ, Dodin P, Tremblay-Racine F, Elwood C, Money D, Boucoiran I. Cabergoline: a review of its use in the inhibition of lactation for women living with HIV. J Int AIDS Soc. 2019 June. [Accessed on 4th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558502/
3. Pfizer Italia S.r.l. Electronic Medicines Compendium (EMC). [Revised in October 2020] [Accessed on 4th May 2022] https://www.medicines.org.uk/emc/files/pil.1691.pdf
4. Pfizer Italia S.r.L. Health Products Regulatory Authority (HPRA). [Revised in March 2017] [Accessed on 4th May 2022] https://www.hpra.ie/img/uploaded/swedocuments/2189875.PPA1562_108_001.92e3872d-e432-4156-9ec0-f803df81acfe.000001Product%20Leaflet%20Approved.170406.pdf
5. Cabergoline tablet. DailyMed: National Library of Medicine: National Institute of Health. [Revised in July 2020] [Accessed on 4th May 2022] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=74b61e8a-7ae9-4996-85ec-df23c56de16f
6. Teva UK Ltd. Cabergoline. [Revised in October 2021] [Accessed on 4th May 2022] https://products.tevauk.com/mediafile/id/51637.pdf
Useful Diagnostic Tests
- Prolactin
- Smear tests
- Echocardiogram
- Kidney function test
Author Details
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