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Introduction About BIORAN GEL
BIORAN GEL contains diclofenac, which belongs to the group of medicines called Nonsteroidal Anti-Inflammatory Drugs (NSAIDs). It is used to manage pain and inflammation related to muscle and joint injuries (Ex. sprains, strains, bruises, sports injuries, backache), tendonitis (Ex. tennis elbow), osteoarthritis (flexible tissue at the ends of bones wears down), swelling around the elbow or knee, or post-trauma.
If you are using BIORAN GEL for arthritis, your doctor may want to review your management regularly. If the pain and swelling do not improve within 7 days or if they worsen, inform your doctor. Avoid smoking or going near naked flames, as there might be a risk of severe burns.
BIORAN GEL is not recommended for use in patients having kidney failure, severe joint pain of recent onset (unrelated to an injury or period of overuse), illness, fever, or any other symptoms along with the pain. Before using BIORAN GEL, inform your doctor if you have any stomach or bowel ulcer, asthma, liver, kidney, or bleeding problems.
BIORAN GEL is not recommended for use in pregnancy (especially in the last 3 months) and should be used in breastfeeding women only under medical advice. BIORAN GEL is not recommended for use in children and adolescents (below 14 years of age).
Be cautious when sunbathing or using sun lamps, as your skin may be more sensitive to sunlight. The most common side effects of using BIORAN GEL are skin rash, itching, reddening of the skin, etc. Call your doctor if any of the symptoms worsen.
Uses Of BIORAN GEL
Manages pain and inflammation related to:
- Muscle and joint injuries (Ex. sprains, strains, bruises, sports injuries, backaches)
- Tendonitis (Ex. tennis elbow)
- Osteoarthritis
- Swelling around elbow or knee
- Post-trauma
How BIORAN GEL Works
BIORAN GEL relieves pain and inflammation by inhibiting certain enzymes (COX-1 and COX-2) involved in the synthesis of prostaglandins (chemicals responsible for inducing pain and inflammation).
How to use BIORAN GEL
Apply BIORAN GEL as advised by your physician. It is for external use only. Apply on healthy skin only. Wash your hands before and after application. Do not cover the applied area with occlusive bandages or plasters. Do not apply BIORAN GEL on injured or infected skin.
In case of accidental contact with eyes, mucous membranes, or injured skin, wash the affected area with running water. If the irritation persists, call your doctor. Your doctor will decide a proper dose and duration for you depending upon your age, body weight, and severity of your condition.
Side Effects Of BIORAN GEL
Common
- Skin rash, itching, reddening, burning sensation, or scaling of the skin
- Skin disorder (eczema)
- Skin inflammation in the applied area (rash, swelling, or papules)
Rare
- Bullous dermatitis (extensive skin changes with the appearance of redness, scaling, and large bubbles)
- Increased sun sensitivity (itching, swelling, blistering)
Stop using BIORAN GEL and contact your doctor immediately if you experience any of the following side effects:
- Allergic reaction (skin rash with blisters, hives, wheezing, breathlessness, chest tightness, swollen face, lips, tongue, or throat)
- Serious skin reactions (Ex. exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis)
How To Manage Side Effects
Skin rash Or Itching
Avoid hot showers, as they can further irritate your skin. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. If the symptom persists, contact your doctor.
Warning & Precautions
Pregnancy
Monitoring requiredBIORAN GEL is not recommended for use in pregnancy (during the last 3 months). BIORAN GEL should be used only under medical advice during the first 6 months of pregnancy. Consult your doctor for advice.
Breastfeeding
Monitoring requiredBIORAN GEL should only be used under medical advice during breast-feeding as it passes into breast milk in small amounts. However, prolonged application on the breasts of nursing mothers or elsewhere on large areas of skin should be avoided. Consult your doctor for advice.
Driving and Using Machines
SafeBIORAN GEL generally does not affect your ability to drive or use machines.
Kidney
Consult your doctorBIORAN GEL is not recommended for use in patients with kidney failure. BIORAN GEL should be used with caution in patients having other kidney problems. Consult your doctor for advice.
Liver
Use with CautionBIORAN GEL should be used with caution in patients having liver problems. Consult your doctor for advice.
Allergy
ContraindicatedBIORAN GEL is not recommended for use if you are allergic to diclofenac, aspirin, ibuprofen, other NSAIDs, peanuts, soy, or any of the other ingredients of this medicine.
Lungs
Use with CautionBIORAN GEL should be used with caution in patients having asthma. Consult your doctor for advice.
Use In Pediatrics
ContraindicatedBIORAN GEL is not recommended for use in children (under 14 years of age). Consult your child’s doctor for advice.
Use In Geriatrics
Use with CautionBIORAN GEL should be used with caution in elderly patients. Consult your doctor for advice.
Others
BIORAN GEL is not recommended for use if you:
- Have severe joint pain of recent onset (unrelated to an injury or period of overuse)
- Feel ill, have a fever, or any other symptoms along with the pain
Before using BIORAN GEL, inform your doctor if you:
- Have or had stomach or bowel ulcers
- Have a tendency for bleeding
- Have inflammatory bowel disease
- Are dehydrated
Interactions
A. Drug-Drug Interactions:
Before using BIORAN GEL, inform your doctor if you are taking any of the following medicines:
- Medicines used to remove excess water from the body (Ex. spironolactone, furosemide)
- Medicines used to manage high blood pressure and other heart problems (Ex. captopril, atenolol, metoprolol, digoxin)
- Other medicines used for pain relief (Ex. aspirin, ibuprofen)
Overdosage:
If you or anyone else accidentally use too much of BIORAN GEL, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Diclofenac |
| Pharmacological Category | : | Cyclooxygenase Inhibitors |
| Therapeutic Indication | : | Pain and inflammation |
| Dosage Forms | : | Tablet, Capsule, Dispersible tablet, Injection, Infusion, PFS, Eye Drops, Gel, Nano Gel, Spray, Solution, Topical Solution, Liniment, Sachet, Patch, Suppository, Ointment |
More Information
Storage
- Keep BIORAN GEL out of reach of children
- Store BIORAN GEL below 30°C
FAQs About BIORAN GEL
Q: Can I use BIORAN GEL if I am taking paracetamol?
A: It is safe to use BIORAN GEL with paracetamol, but this does not necessarily mean no interactions exist. Consult your doctor before taking any other medicine with BIORAN GEL, especially other similar painkillers (NSAIDs).
Q: What if I forget to apply a dose of BIORAN GEL?
A: If you forget to apply a dose of BIORAN GEL, do it as soon as you remember. However, omit that dose if it's almost time for the next one. Do not apply a double quantity of BIORAN GEL to make up for the missed dose.
Q: Can I stop using BIORAN GEL on my own?
A: BIORAN GEL management can be stopped at any time without requiring special care. However, you may feel pain or swelling in the affected area again. If you have any further queries on the use of this medicine, ask your doctor.
Q: Is BIORAN GEL safe to use in asthmatic patients?
A: BIORAN GEL should be used with caution if you have or ever had asthma. Consult your doctor for advice. Your doctor will determine a proper dose of BIORAN GEL or select a suitable alternative management for you according to your condition.
Q: Can BIORAN GEL be used during pregnancy?
A: BIORAN GEL must not be used during the last 3 months of pregnancy, as it could harm your unborn baby or cause problems at delivery. It should only be used under medical advice during the first 6 months of pregnancy, and the dose and duration should be kept as small as possible. If you are pregnant, think you may be pregnant, or are planning for a baby, consult your doctor before using it.
Q: What if I accidentally swallow BIORAN GEL?
A: If you or anyone else accidentally swallow BIORAN GEL, see your doctor immediately or go to your nearest hospital. Take your medicine with you for the doctor to know what you’ve ingested.
Q: What is BIORAN GEL used for?
A: BIORAN GEL is used to manage pain and inflammation related to muscle and joint injuries (Ex. sprains, strains, bruises, sports injuries, backache), tendonitis (Ex. tennis elbow), osteoarthritis (flexible tissue at the ends of bones wears down), swelling around the elbow or knee, or post-trauma.
Q: How should I use BIORAN GEL?
A: Apply BIORAN GEL as advised by your physician. It is for external use only. Apply on healthy skin only. Wash your hands before and after application. Do not cover the applied area with occlusive bandages or plasters. Do not apply BIORAN GEL on injured or infected skin. In case of accidental contact with eyes, mucous membranes, or injured skin, wash the affected area with running water. If the irritation persists, call your doctor. Your doctor will decide a proper dose and duration for you depending upon your age, body weight, and severity of your condition.
Q: What are the side effects of using BIORAN GEL?
A: The most common side effects of using BIORAN GEL are skin rash, itching, reddening of the skin, etc. Call your doctor if any of the symptoms worsen.
Q: Who should not use BIORAN GEL?
A: BIORAN GEL is not recommended for use if you are allergic to Diclofenac, aspirin, ibuprofen, other NSAIDs, peanuts, soya, or have kidney failure, severe joint pain of recent onset (unrelated to an injury or period of overuse), feel ill, have fever, or any other symptoms along with the pain.
Q: What precautions must be taken while using BIORAN GEL?
A: BIORAN GEL should be used with caution in patients having other kidney problems, liver problems, asthma, stomach or bowel ulcers, tendency for bleeding, inflammatory bowel disease, and dehydration.
References
1. KD. Tripathi. Nonsteroidal anti-inflammatory drugs and antipyretic analgesics. Essentials of Medical Pharmacology. Eighth Edition. 2019. Page – 221.
2. Sharma Y, Philip VM, Sharma S. Prospective, open-label, randomized, parallel group, comparative clinical study of two topical formulations of diclofenac diethylamine in the treatment of acute painful musculoskeletal conditions. Journal of Marine Medical Society. March 2020. [Accessed on 26th July 2024] https://www.marinemedicalsociety.in/article.asp?issn=0975-3605;year=2020;volume=22;issue=1;spage=35;epage=39;aulast=Sharma
3. Bariguian Revel, F., Fayet, M., & Hagen, M. Topical Diclofenac, an Efficacious Treatment for Osteoarthritis: A Narrative Review. NIH National Library of Medicine, National Center for Biotechnology Information. Pubmed Central. June 2020. [Accessed on 26th July 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211216/
4. Amdeepcha Limited,. Electronic Medicines Compendium (EMC). [Revised in November 2021] [Accessed on 26th July 2024] https://www.medicines.org.uk/emc/files/pil.10950.pdf
5. Laboratórios Basi – Indústria Farmacêutica, S.A. Electronic Medicines Compendium (EMC). [Revised in July 2021] [Accessed on 26th July 2024] https://www.medicines.org.uk/emc/files/pil.12073.pdf
6. GlaxoSmithKline Consumer Healthcare (UK). Electronic Medicines Compendium (EMC). [Revised in March 2020] [Accessed on 26th July 2024] https://www.medicines.org.uk/emc/files/pil.366.pdf
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Liver Function Test (LFT)
- Rheumatoid Factor (RF)/RA Test Rheumatoid Arthritis Factor, Qualitative
- Basic Arthritis Care
- Extended Arthritis Care
- Advance Bone Care
- Comprehensive Bone Care
- Frequent Pain Check Package
- Autoimmune Arthritis Panel
- Arthritis Profile – Advanced
Author Details
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
