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Introduction About BENFORCE M TABLET
BENFORCE M TABLET is a combination of Alpha Lipoic Acid and Metformin, which belongs to the group of medicines called Antidiabetic agents. It is used in the management of diabetes mellitus and polycystic ovarian disease.
During management with BENFORCE M TABLET, your doctor will conduct a blood test to check for blood sugar levels and kidney function.
BENFORCE M TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Inform your doctor if you are pregnant or planning to become pregnant before taking this medicine.
BENFORCE M TABLET is not recommended for use if you have severely reduced kidney function, liver disease, acute heart failure, a recent history of heart attack, or severe problems with blood circulation (such as shock) or have breathing difficulties. Consult your doctor before taking it.
The most common side effects of taking BENFORCE M TABLET are nausea, vomiting, diarrhea, abdominal pain, loss of appetite, changes in taste, and skin rash. Consult your doctor if any of the side effects worsen.
Uses Of BENFORCE M TABLET
- To manage type II diabetes mellitus and polycystic ovarian disease
How BENFORCE M TABLET Works
BENFORCE M TABLET effectively controls blood glucose levels and polycystic ovarian disease, where metformin works by decreasing the production of glucose in the liver, decreasing the intestinal absorption of glucose, increasing insulin sensitivity, and allowing better glucose uptake and utilization by the body. Alpha-lipoic acid is an antioxidant that helps protect cells from free radical damage. It helps improve insulin resistance and enhance glucose uptake by the body.
How to use BENFORCE M TABLET
Take BENFORCE M TABLET, preferably with meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition.
Side Effects Of BENFORCE M TABLET
Common
- nausea, vomiting, diarrhea, abdominal pain, and loss of appetite
- changes in taste
- skin rash
- symptoms of low vitamin B12 levels in the blood may include extreme tiredness, a sore and red tongue (glossitis), pins and needles (paraesthesia), or pale or yellow skin
Stop taking BENFORCE M TABLET and consult your doctor immediately if you experience any of the following side effects:
- The symptoms of lactic acidosis are vomiting, abdominal pain, muscle cramps, a general feeling of not being well with severe tiredness, difficulty breathing, reduced body temperature, and a slow heartbeat
- Symptoms of low blood sugar levels such as headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery or light-headedness
How To Manage Side Effects
Diarrhea
Drink lots of fluids, such as water or fruit juices, to keep yourself hydrated. Do not take any medicine on your own to manage diarrhea. Contact your doctor if your diarrhea does not improve.
Nausea And Vomiting
Take BENFORCE M TABLET with a meal. Stick to simple meals. Avoid eating oily or spicy food. Contact your doctor if your nausea and vomiting do not improve.
Stomach Pain
Rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Keep a heating pad on your stomach. Do not self-manage on your own, consult your doctor if the symptom does not improve on its own.
Warning & Precautions
Pregnancy
Consult your doctorInform your doctor if you are pregnant or planning to have a baby before taking this medicine.
Breastfeeding
ContraindicatedBENFORCE M TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or operate any machinery if you have weakness, dizziness, increased sweating, a fast heartbeat, visual problems, or difficulty in concentration after taking BENFORCE M TABLET.
Alcohol
Consult your doctorAvoid excessive consumption of alcohol, as it may increase the risk of lactic acidosis.
Kidney
ContraindicatedBENFORCE M TABLET is not recommended for use if you have severely reduced kidney function. Consult your doctor before taking it.
Liver
ContraindicatedBENFORCE M TABLET is not recommended for use if you have liver disease. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take BENFORCE M TABLET if you are allergic to metformin, alpha-lipoic acid, or any of the other ingredients in this medicine.
Heart Disease
ContraindicatedBENFORCE M TABLET is not recommended for use if you are managed for acute heart failure, a recent history of heart attack, or severe problems with blood circulation (such as shock) or have breathing difficulties. Consult your doctor before taking it.
Use In Pediatrics
Consult your doctorThere is no information on the use of BENFORCE M TABLET in children. Consult your doctor for advice.
Use In Geriatrics
Use with CautionBENFORCE M TABLET should be used with caution only in elderly patients aged 65 years and older. Consult your doctor before taking it.
Others
BENFORCE M TABLET is not recommended for use if you:
- have uncontrolled diabetes mellitus with lactic acidosis, or ketoacidosis
- have dehydration due to severe diarrhea and vomiting
- have severe infections in the lungs and kidneys
- are scheduled for lab testing
- are planned for surgery
Before taking BENFORCE M TABLET, inform your doctor if you:
- have thyroid disease
- have vitamin B1 deficiency
Interactions
A. Drug-Drug interactions:
Before taking BENFORCE M TABLET, inform your doctor if you are taking any of the following medicines, such as:
- sulphonylureas, insulin, and meglitinides (other medicines used to manage diabetes) Ex. glimepiride, repaglinide
- medicines that increase urine production (diuretics) Ex. chlorothiazide
- beta-2 agonists such as salbutamol or terbutaline (used to manage asthma)
- corticosteroids (used to manage severe inflammation of the skin or asthma), Ex. dexamethasone
- verapamil (medicine used to manage blood pressure)
- rifampicin (a medicine used to manage tuberculosis)
- cimetidine (a medicine used to manage stomach problems)
- dolutegravir (a medicine used to manage viral infections)
- ranolazine (medicine used to manage chest pain)
- trimethoprim, neomycin, and aminosalicylic acid (medicine used to manage bacterial infections)
- vandetanib, crizotinib, and olaparib (medicine used to manage cancer)
- isavuconazole (a medicine used to manage fungal infections)
- medicines used to manage pain and inflammation (NSAIDs and COX-2-inhibitors, such as ibuprofen and celecoxib)
- certain medicines for the management of high blood pressure (ACE inhibitors and angiotensin II receptor antagonists) Ex. enalapril, candesartan
- medicines to manage hypothyroidism Ex. levothyroxine
Overdosage:
If you or anyone else accidentally took more BENFORCE M TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage may cause lactic acidosis, and symptoms include vomiting, abdominal pain with muscle cramps, a general feeling of not being well with severe tiredness, and difficulty breathing. Further symptoms include a reduced body temperature and heartbeat.
Synopsis
| Drug | : | Alpha lipoic acid and Metformin |
| Pharmacological Category | : | Antioxidants, Biguanides |
| Therapeutic Indication | : | Type II diabetes mellitus, Polycystic Ovarian Disease |
| Dosage Forms | : | Tablet |
More Information
- Keep BENFORCE M TABLET out of the sight and reach of children
- Store BENFORCE M TABLET below 30°C
FAQs About BENFORCE M TABLET
Q: What if I forget to take BENFORCE M TABLET?
A: If you forgot to take a dose of BENFORCE M TABLET, take it as soon as you remember. However, if it is time for the next dose of BENFORCE M TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of BENFORCE M TABLET to compensate for the missed ones.
Q: Is BENFORCE M TABLET safe in pregnancy?
A: Inform your doctor if you are pregnant or planning to become pregnant before taking this medication.
Q: Who should not take BENFORCE M TABLET?
A: BENFORCE M TABLET is not recommended for use if you have severely reduced kidney function, liver disease, acute heart failure or a recent history of heart attack, or severe problems with blood circulation (such as shock) or have breathing difficulties, have uncontrolled diabetes mellitus with lactic acidosis or ketoacidosis, have dehydration due to severe diarrhea and vomiting, or have severe infections in the lungs and kidneys. Consult your doctor before taking it.
Q: What are the side effects of taking BENFORCE M TABLET?
A: The most common side effects of taking BENFORCE M TABLET are nausea, vomiting, diarrhea, abdominal pain, loss of appetite, changes in taste, and skin rash. Consult your doctor if any of the side effects worsen.
Q: What should I avoid while taking BENFORCE M TABLET?
A: Avoid excessive consumption of alcohol while taking BENFORCE M TABLET, as it may increase the risk of lactic acidosis.
References
1. KD. Tripathi. Insulin, Oral Antidiabetic Drugs and Glucagon. Essentials of medical pharmacology. Eight edition. 2019. Page – 299.
2. Guarano A, Capozzi A, Cristodoro M, Di Simone N, Lello S. Alpha Lipoic Acid Efficacy in PCOS Treatment: What Is the Truth? Nutrients. 2023. [Accessed on 3rd January 2024] https://doi.org/10.3390/nu15143209
3. A.S. Laganà, N. Monti, V. Fedeli, G. Gullo, M. Bizzarri. Does Alpha-lipoic acid improve effects on polycystic ovary syndrome? European review for Medical and Pharmacological Sciences.2022. [Accessed on 3rd January 2024] https://www.europeanreview.org/article/28116
4. Brown & Burk UK Ltd. Electronic Medicines Compendium (EMC) [Revised in May 2022] [Accessed on 3rd January 2024] https://www.medicines.org.uk/emc/files/pil.10760.pdf
5. Metmin A Tablet (Methylcobalamin+Alpha lipoic acid). Jenburkt Pharmaceuticals Ltd. [Accessed on 3rd January 2024] https://jenburkt.com/brands/metmin
6. Drugs.com. Alpha lipoic acid. [Accessed on 3rd January 2024] https://www.drugs.com/mtm/alpha-lipoic-acid.html, https://www.drugs.com/npp/alpha-lipoic-acid.html
Useful Diagnostic Tests
- HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
- Blood Glucose Fasting (FBS)
- Random Blood Sugar (RBS)
- Post Prandial Blood Sugar (PPBS)
- Insulin-Fasting
- Insulin Postprandial (PP)
- Vital Diabetes Care
- Extended Diabetes Care
- Advance Diabetes Care
- Comprehensive Diabetes Care
Author Details
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
