It contains a medicine called azithromycin, which belongs to a group of medicines called Macrolide Antibiotics. It works by preventing the growth of bacteria and helps clear up the infection.

Uses Of AZITHRAL INFUSION

• Manage localized bacterial infections affecting different parts of the body
• Manage serious infections (such as pneumonia, pelvic infections) or when oral management is not possible in affected individuals

How AZITHRAL INFUSION Works

AZITHRAL INFUSION works by inhibiting bacterial protein synthesis (essential for the bacteria's growth), which results in its destruction, thus managing its growth and spread of infection in affected individuals.

How to use AZITHRAL INFUSION

• This medicine will be given to you only by a doctor or a nurse into a vein as an intravenous infusion.
• Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

Side Effects Of AZITHRAL INFUSION

Common Side Effects of AZITHRAL INFUSION:

• stomach cramps, nausea, vomiting, diarrhea, flatulence
• dizziness, headache
• numbness/pickling sensation
• loss of appetite, taste disturbance
• visual disturbances, deafness
• joint pain
• tiredness, weakness

Stop receiving AZITHRAL INFUSION and contact your physician immediately if you experience any of the following side effects:

• signs of allergic reactions such as sudden wheezing, difficulty breathing, swelling of eyelids, face, or lips, rash, and/or itching (affecting the whole body)
• signs of serious bowel inflammation, such as severe/prolonged diarrhea, which may have blood or mucus in it, during/after management
• rapid or irregular heartbeat and low blood pressure

Warning & Precautions

Pregnancy

Use with Caution

AZITHRAL INFUSION should be used with caution during pregnancy and in women planning for pregnancy.

Breastfeeding

Use with Caution

AZITHRAL INFUSION should be used with caution in breastfeeding women.

Driving and Using Machines

Use with Caution

Do not drive or operate machines if AZITHRAL INFUSION affects your ability to drive or operate machines.

Kidney

Use with Caution

AZITHRAL INFUSION should be used with caution in patients with kidney problems.

Liver

Use with Caution

AZITHRAL INFUSION should be used with caution in patients with liver problems.

Allergy

Contraindicated

Do not receive AZITHRAL INFUSION if you are allergic (hypersensitive) to azithromycin, other antibiotics such as erythromycin/clarithromycin (macrolides), ketolides, and/or any other ingredients of this medicine.

Heart Disease

Use with Caution

AZITHRAL INFUSION should be used with caution in patients with abnormal heart rhythm problems (such as long QT syndrome).

Use In Pediatrics

Contraindicated

AZITHRAL INFUSION is not recommended for use in children and adolescents (below 18 years).

Use In Geriatrics

Use with Caution

AZITHRAL INFUSION should be used with caution in elderly patients (aged above 65 years).

Interactions

A. Drug-Drug interactions:

Tell your doctor if you have recently taken any other medicines, including medicines obtained without a prescription, vitamin supplements, or herbal products:

• ergotamine (medicine used to manage migraine)
• warfarin (medicine used to manage blood clots)
• ciclosporin (used to manage transplanted organ rejection)
• antacids (used to manage indigestion) Ex. aluminium hydroxide, magnesium carbonate
• digoxin (used to manage heart failure)
• colchicine (used for gout and familial Mediterranean fever)
• terfenadine (used for skin allergy)
• hydroxychloroquine, chloroquine (medicines used to manage malaria)
• nelfinavir, zidovudine (medicines used in the management of HIV)
• rifabutin (used for HIV/tuberculosis)
• theophylline (used for breathing problems)

Overdosage:

AZITHRAL INFUSION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.

Synopsis

More Information

FAQs About AZITHRAL INFUSION

Q: What is AZITHRAL INFUSION used for?

A: AZITHRAL INFUSION is used to manage localized infections caused by bacteria affecting different parts of the body. It is also used to manage serious infections such as pneumonia (lung infection), pelvic infections, or when oral management is not possible in affected individuals.

Q: How does AZITHRAL INFUSION work?

A: AZITHRAL INFUSION works by inhibiting bacterial protein synthesis (essential for the bacteria to grow), which results in its destruction, thus managing its growth and spread of infection in affected individuals.

Q: What are the most common side effects of receiving AZITHRAL INFUSION?

A: The most common side effects of receiving AZITHRAL INFUSION are stomach cramps, nausea, vomiting, diarrhea, flatulence, dizziness, and/or headache. Consult your doctor if any of the symptoms worsen.

Q: Can AZITHRAL INFUSION be used during pregnancy?

A: Azithromycin can be used during pregnancy, but only with caution and under the guidance of a doctor.

Q: Can I use AZITHRAL INFUSION if I’m breastfeeding?

A: Azithromycin can be used with caution while breastfeeding. Consult your doctor first.

Q: How AZITHRAL INFUSION is given?

A: AZITHRAL INFUSION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

Q: Is AZITHRAL INFUSION safe for kids?

A: AZITHRAL INFUSION is not recommended for use in children and adolescents (below 18 years).

Q: Who should not use AZITHRAL INFUSION?

A: Do not receive AZITHRAL INFUSION if you are allergic (hypersensitive) to azithromycin, other antibiotics such as erythromycin/clarithromycin (macrolides), ketolides, and/or any other ingredients of this medicine.

Q: What should I tell my doctor before using AZITHRAL INFUSION?

A: Before receiving AZITHRAL INFUSION, inform your doctor if you suffer from neurological/psychiatric diseases or have myasthenia gravis (a condition marked by weak muscles), kidney problems, liver problems, or abnormal heart rhythm problems (such as long QT syndrome).

Q: What should I do if I miss a dose of AZITHRAL INFUSION?

A: Since this medicine is administered by healthcare professionals, missed doses are unlikely. However, inform your doctor if you have any concerns.

References

1. Antibiotics; Urinary Antiseptics. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 755

2. Michael J. Parnham, Vesna Erakovic Haber, Evangelos J. Giamarellos-Bourboulis, Gianpaolo Perletti, Geert M. Verleden, Robin Vos. Azithromycin: mechanisms of action and their relevance for clinical applications. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. August 2014. [Accessed on 30th September 2024]  click here

3. Eric M. Mortensen, Ethan A. Halm, Mary Jo Pugh, Laurel A. Copeland, Mark Metersky, Michael J. Fine, Christopher S. Johnson, Carlos A. Alvarez, Christopher R. Frei, Chester Good, Marcos I. Restrepo, John R. Downs, and Antonio Anzueto, Association of azithromycin with mortality and cardiovascular events among older patients hospitalized with pneumonia. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. June 2015. [Accessed on 30th September 2024]  click here

4. Anfarm Hellas S.A. Electronic Medicines Compendium (EMC). [Revised in December 2021] [Accessed on 30th September 2024]  click here

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Author Details

Written By Srilekha. R - B.Pharm

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 23 Nov 2024 | 05:03 PM(IST)