Introduction About ARRENO CAPSULE

ARRENO CAPSULE is a combination of Aspirin and Dipyridamole which belongs to the group of medicines called Antiplatelet agents. It is used to lower the risk of stroke in people who have had a mini-stroke (transient ischemic attack or TIA) or previous stroke due to a blood clot and are at high risk for another stroke.

A stroke occurs when a blood vessel that carries oxygen and nutrients to the brain is either blocked by a clot or bursts (or ruptures). When that happens, part of the brain cannot get the blood (and oxygen) it needs, so it and brain cells die.

Transient ischemic attack is a stroke that lasts only a few minutes. It happens when the blood supply to part of the brain is briefly blocked. Symptoms of a TIA are like other stroke symptoms, but do not last as long. It is also called as TIA, mini stroke.

Before taking ARRENO CAPSULE inform your doctor if you have heart disease, liver disease or kidney disease. Pregnant and breastfeeding women should consult their doctor before taking ARRENO CAPSULE.

The most common side effects ARRENO CAPSULE are headache, stomach upset, diarrhoea, nausea, vomiting, heartburn, dizziness. Consult your doctor if any of the above side effects worsen or persists for a longer duration.

Uses Of ARRENO CAPSULE

• Used to lower the risk of stroke in patients who had transient ischemia of the brain of complete ischemic stroke due to thrombosis

How ARRENO CAPSULE Works

ARRENO CAPSULE is a combination of Aspirin and Dipyridamole which works by stopping platelets from clumping together. This helps to manage the platelets from forming blood clots, which can lodge in the brain and cause a certain type of stroke (ischemic stroke).

How to use ARRENO CAPSULE

Take ARRENO CAPSULE as directed by your physician. Swallow the medicine and do not crush or chew the medicine. Your doctor will decide the correct dose for you depending upon your age, body weight and disease condition.

Side Effects Of ARRENO CAPSULE

How To Manage Side Effects

Headache:  

Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the head if required. Do not consume too much of alcohol. Consult your doctor if the symptom did not improve.

Stomach upset:

Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. Do not self-manage on your own and consult your doctor if the symptom did not improve on its own.

Diarrhoea:

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for managing diarrhoea. Consult your doctor if the symptom did not improve.

Nausea and Vomiting:

Try to take this medicine with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.

Warning & Precautions

Pregnancy

ARRENO CAPSULE is not recommended for use in pregnant women (especially last trimester of pregnancy). Consult your doctor before taking ARRENO CAPSULE.

Breastfeeding

ARRENO CAPSULE is not recommended for use in breastfeeding women. Consult your doctor before taking ARRENO CAPSULE.

Driving and Using Machines

Do not drive or operate any heavy tools or machines since it may cause dizziness.

Alcohol

Avoid consumption of alcohol while taking this medicine as it could increase the risk of stomach bleeding.

Kidney

ARRENO CAPSULE should be used with caution in patients with kidney disease. Consult your doctor before taking ARRENO CAPSULE.

Liver

ARRENO CAPSULE should be used with caution in patients with liver disease. Consult your doctor before taking ARRENO CAPSULE.

Allergy

Do not take this medicine if you are allergic (hypersensitive) to Aspirin or Dipyridamole or other salicylates such as choline salicylate or any other non-steroidal anti-inflammatory medicines.

Lungs

ARRENO CAPSULE is not recommended for use in patients with respiratory conditions such as asthma with runny nose and nasal polyps, history of worsening breathing. Consult your doctor before taking ARRENO CAPSULE.

Heart Disease

ARRENO CAPSULE should be used with caution in patients with heart problems (such as angina, heart attack). Consult your doctor before taking ARRENO CAPSULE.

Interactions

A. Drug-Drug interactions:

Before taking ARRENO CAPSULE inform your doctor if you are taking any of the following medicine:

• medicine used for high blood pressure, irregular heartbeat, or heart failure
• acetazolamide (used to manage glaucoma)
• any blood thinner medicines (Ex. warfarin/dabigatran, riociguat, clopidogrel)
• medicine used for seizures or fits
• medicine used for Alzheimer’s disease
• methotrexate (used for cancer)
• aspirin or a non-steroidal anti-inflammatory drug (NSAIDS) such as ibuprofen/naproxen
• medicine used for diabetes
• probenecid (used to manage gout)
• corticosteroids such as prednisone
• mifepristone (used to terminate pregnancy)
• ginkgo biloba

Overdosage:

If you or anyone else took too much of ARRENO CAPSULE, contact your doctor immediately or go to a hospital straight away. Symptoms of overdosage includes warm feeling or flushing, sweating, restlessness, weakness or dizziness, fast heart rate, ringing in the ears, passing out or trouble breathing.  

Synopsis

More Information

• Keep ARRENO CAPSULE out of reach of children
• Store at room temperature

FAQs About ARRENO CAPSULE

Q: Can ARRENO CAPSULE be taken at night?

A: Always take ARRENO CAPSULE as advised by your physician. Your doctor will prescribe a suitable dose, frequency, and time for you depending upon your age and existing disease condition. Consult your doctor for more information regarding the direction of use.

Q: Can I take paracetamol along with ARRENO CAPSULE?

A: Avoid concomitant use of NSAIDS like paracetamol or ibuprofen while taking this medicine, because it may increase of bleeding. Consult your doctor for an alternative pain relief medicine.

Q: Can ARRENO CAPSULE be used in elderly patients?

A: Yes, ARRENO CAPSULE should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking ARRENO CAPSULE.

Q: Can ARRENO CAPSULE be used in pregnancy?

A: No, ARRENO CAPSULE is not recommended for use in pregnant women (especially last trimester of pregnancy). Consult your doctor before taking ARRENO CAPSULE.

References

1. KD. Tripathi. Drugs Affecting Coagulation, Bleeding and Thrombosis. Essentials of medical pharmacology. Seventh edition. 2013. Page – 629.

2. Cathie Sudlow, clinical senior lecturer and honorary consultant neurologist. Give dipyridamole with aspirin instead of aspirin alone to prevent vascular events after ischaemic stroke or TIA. NCBI; PMC US National Library of Medicine, National Institute of Health. April 2007. [Accessed 29 Mar 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1857795/

3. Webmd.com. Aspirin-Dipyridamole. [Accessed 29 Mar 2022] https://www.webmd.com/drugs/2/drug-17175/aspirin-dipyridamole-oral/details

4. Dr. Reddy’s Laboratories Inc., [Revised on May 2021] [Accessed 29 Mar 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=92222dd3-7802-2a03-7d30-58cf192cc33e

5. Boehringer Ingelheim Pharmaceuticals, Inc; U.S. Food & Drug Administration. [Revised on Sep 2012] [Accessed 29 Mar 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020884s030lbl.pdf