Introduction About AMPILOX KID TABLET

AMPILOX KID TABLET is a combination of Ampicillin and Cloxacillin which belongs to the group of medicines called Penicillin Antibiotics. It is used to manage respiratory tract infections like bronchopneumonia, acute exacerbations of chronic bronchitis, post-operative wound infections, postoperative pulmonary infections, puerperal fever and other infections such as septicaemia, pelvic infections, urinary tract infections, skin and soft tissue infections, and gastrointestinal infections, bone infections like Ex. osteomyelitis, ear, nose and throat infections.

Before taking AMPILOX KID TABLET inform your doctor if you have liver or kidney disease. AMPILOX KID TABLET is generally not recommended for use in pregnant women unless clearly necessary. Contact your doctor before taking it.

AMPILOX KID TABLET is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking.

AMPILOX KID TABLET is not recommended for use in neonates with jaundice and should be used with caution in children. Contact your doctor before taking.

AMPILOX KID TABLET should be used with caution in elderly patients (aged above 65 years). Contact your doctor before taking.

The most common side effects of this medicine are nausea, vomiting, diarrhoea, stomach pain or stomach upset and skin rash. Contact your doctor if any of the symptoms worsen.

Uses Of AMPILOX KID TABLET

It is used to manage:

• infected wounds or lung infections following surgery
• respiratory tract infections
• fever associated with a bacterial infection

How AMPILOX KID TABLET Works

AMPILOX KID TABLET is a combination of Ampicillin and cloxacillin where ampicillin (has a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria. It acts through the inhibition of cell wall mucopeptide biosynthesis during the stage of active multiplication.) Cloxacillin manages bacteria from reproducing, which allows your body to fight only the existing bacteria.

How to use AMPILOX KID TABLET

Take AMPILOX KID TABLET as advised by your physician.

For Tablet, Capsule: Swallow AMPILOX KID TABLET with a glass of water. Do not crush or chew the medicine.

For Dispersible Tablet: Disperse the medicine in the specified quantity of water as mentioned on the label. Consume the medicine immediately after reconstitution.

Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight and severity of the infection.

Side Effects Of AMPILOX KID TABLET

How To Manage Side Effects

Nausea or Vomiting:

Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods.

Diarrhoea:

Drink lots of fluids, such as water or fruit juices to keep you hydrated. Do not take any medicine on your own for managing diarrhoea. Contact your doctor if the symptom did not improve.

Stomach pain:

Try to rest and relax. Eat small meals but take them frequently. Keep a heating pad on your stomach. If the symptom does not improve, contact your doctor.

Warning & Precautions

Pregnancy

There is no adequate human data on use during pregnancy. However, studies have not identified any risk to pregnancy or embryo-foetal development. Contact your doctor before taking.

Breastfeeding

There is no adequate human data on use during lactation. Contact your doctor before taking.

Driving and Using Machines

AMPILOX KID TABLET has no effects on the ability to drive and use machinery. Contact your doctor before taking.

Kidney

AMPILOX KID TABLET should be used with caution in patients with kidney disease. Contact your doctor before taking.

Liver

AMPILOX KID TABLET should be used with caution in patients with liver disease. Contact your doctor before taking.

Allergy

Do not take AMPILOX KID TABLET if you are allergic to Ampicillin, Cloxacillin or beta-lactam antibiotics (Ex. penicillin, cephalosporins) or other ingredients of this medicine.

Interactions

A. Drug-Drug interactions:

Inform your physician if you are taking:

• medicines which inhibit the bacteria growth (Ex. chloramphenicol, erythromycin and tetracyclines and sulphonamides)
• medicines used to gout (Ex. probenecid, allopurinol)
• medicines used to manage pregnancy (Ex. oral contraceptives)
• acetylsalicylic acid (medicine used to manage blood clots)

Overdosage:

If you or anyone else accidentally took too much of this medicine, consult your doctor immediately. Symptoms of overdose are nausea, vomiting and diarrhoea.

Synopsis

More Information

• Keep out of reach of children
• Store at room temperature

FAQs About AMPILOX KID TABLET

Can I use AMPILOX KID TABLET for cold?

No. AMPILOX KID TABLET does not manage cold or viral infections. It is used to manage bacterial infections. Contact your doctor before taking.

Who should not use AMPILOX KID TABLET?

AMPILOX KID TABLET is not recommended for patients with allergic history to ampicillin, cloxacillin or beta-lactam antibiotics like penicillin, cephalosporins and patients with infectious mononucleosis, acute or chronic leukaemia, pregnant women unless clearly necessary, and breastfeeding women. Contact your doctor before taking.

Does AMPILOX KID TABLET cause liver damage?

Yes. AMPILOX KID TABLET may cause liver damage. Contact your doctor if you experience any unusual symptoms such as yellowish discoloration of skin and whites of eye (jaundice), change in urine and stool colour.

How AMPILOX KID TABLET works?

AMPILOX KID TABLET is a combination of Ampicillin and cloxacillin where ampicillin (has a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria. It acts through the inhibition of cell wall mucopeptide biosynthesis during the stage of active multiplication.) Cloxacillin manages bacteria from reproducing, which allows your body to fight only the existing bacteria.

Can I use AMPILOX KID TABLET in children?

Yes. AMPILOX KID TABLET should be used with caution in children. Contact your doctor before taking.

References

1. Peechakara BV, Basit H, Gupta M. Mechanism of Ampicillin. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. November 2021. [Accessed on 23rd May 2022] https://www.ncbi.nlm.nih.gov/books/NBK519569/

2. Maxheal pharmaceuticals (India) Ltd. Ampicillin and cloxacillin. [Accessed on 23rd May 2022] https://www.nafdac.gov.ng/wp-content/uploads/Files/SMPC/DEC_21/Greenfield-Ampicillin-and-Cloxacillin-Capsules-500mg.pdf

3. MEDREICH LIMITED. Ampicillin and cloxacillin. [Revised on August 2014] [Accessed on 23rd May 2022] https://gskpro.com/content/dam/global/hcpportal/en_NG/PDF/Home/Products/Ampiclox_GA_03.pdf

4. Ampicillin and cloxacillin. [Revised on April 202] [Accessed on 23rd May 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2904.pdf

5. Ampicillin and cloxacillin. Advacarepharma.com. [Accessed on 23rd May 2022] https://www.advacarepharma.com/en/pharmaceuticals/ampicillin-cloxacillin-capsules

6. Ampicillin and cloxacillin. Centurionhealthcare.com. [Accessed on 23rd May 2022] https://www.centurionhealthcare.com/product-detail/ampicillin-cloxacillin-capsules

7. Ampicillin and cloxacillin. Mims.com. [Accessed on 23rd May 2022] https://www.mims.com/india/drug/info/ampicillin%20+%20cloxacillin?type=full&mtype=generic#dosage

Useful Diagnostic Tests

• Complete blood count
• Kidney function test
• Liver function test