ALPHACEPT M 50 Tablet 10's
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Quality Checked ProductsIntroduction About ALPHACEPT M 50 TABLET
ALPHACEPT M 50 TABLET is used in the management of Benign Prostatic Hyperplasia complicated by an overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency. It is a combination of Mirabegron and Silodosin, which belongs to the group of medicines called Beta-3 adrenergic agonists and Alpha blockers respectively.
ALPHACEPT M 50 TABLET is not recommended for use if you have severe kidney disease, severe liver disease, or severe, uncontrolled high blood pressure. Consult your doctor before taking it. ALPHACEPT M 50 TABLET should be used with caution in patients with mild to moderate kidney and liver disease and ECG abnormalities (QT prolongation). Consult your doctor before taking it. ALPHACEPT M 50 TABLET is not recommended for use by pregnant women unless clearly necessary. ALPHACEPT M 50 TABLET is not recommended for use in breastfeeding women as it may pass into the breast milk. Consult your doctor before taking it.
ALPHACEPT M 50 TABLET is not recommended for use in children and adolescents under 18 years of age since there is no relevant indication for this age group. Consult your doctor before taking the medicine. The most common side effects of taking ALPHACEPT M 50 TABLET are abnormal ejaculation (less or no noticeable semen is released during sex), increased heart rate (tachycardia), urinary tract infections, dizziness, including dizziness when standing up, runny or blocked nose, constipation, and nausea. Consult your doctor if any of the side effects worsen.
Uses Of ALPHACEPT M 50 TABLET
- Used to manage Benign Prostatic Hyperplasia complicated by an overactive bladder
How ALPHACEPT M 50 TABLET Works
ALPHACEPT M 50 TABLET is a combination of Mirabegron and Silodosin. Mirabegron is a beta-3 adrenergic agonist that works by relaxing the muscles around the bladder. This increases the amount of urine that your bladder can hold and manages urgent, frequent, and uncontrolled urination. Silodosin is an alpha blocker that works by relaxing the muscles of the lower urinary tract and helps in relieving symptoms of difficulty urinating, painful urination, urinary frequency, and urgency.
How to use ALPHACEPT M 50 TABLET
Take ALPHACEPT M 50 TABLET as directed by the doctor. Swallow the medicine with a glass of water, and do not crush or chew the medicine. Your doctor will decide the correct dose and duration of management depending on your age, body weight, and disease condition.
Side Effects Of ALPHACEPT M 50 TABLET
Common
- abnormal ejaculation
- increased heart rate
- urinary tract infections
- dizziness
- runny or blocked nose
- constipation
- nausea
Uncommon
- bladder infection
- feeling your heartbeat
- indigestion
- infection of the stomach
- swelling of the joints
- increased blood pressure
- itching, rash, or hives
- dry mouth
- decreased sexual drive
Rare
- swelling of the eyelid
- swelling of the lip
- swelling of the deeper layers of the skin caused by a buildup of fluid
- small purple spots on the skin
- inflammation of small blood vessels mainly affecting the skin
- inability to completely empty the bladder
Stop taking ALPHACEPT M 50 TABLET and consult your doctor immediately if you experience any of the following side effects:
- swelling of the face, lips, tongue, and/or throat, causing difficulty breathing
How To Manage Side Effects
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any machines while you are feeling dizzy. Do not drink alcohol, as it can aggravate your dizziness. Contact your doctor if your dizziness does not improve.
Dry Mouth
Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Consult your doctor if the dry mouth gets worse.
Nausea And Vomiting
Take ALPHACEPT M 50 TABLET with or just after a meal. Stick to simple meals. Avoid eating oily or spicy food. Contact your doctor if your nausea and vomiting do not improve.
Warning & Precautions
Pregnancy
ContraindicatedALPHACEPT M 50 TABLET is not recommended for use in pregnant women. Consult your doctor before taking the medicine.
Breastfeeding
ContraindicatedALPHACEPT M 50 TABLET is not recommended for use in breastfeeding women as it may pass into the breast milk. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or operate heavy machinery if you feel dizziness after taking ALPHACEPT M 50 TABLET.
Kidney
Consult your doctorALPHACEPT M 50 TABLET is not recommended for use if you have severe kidney disease. It should be used with caution in patients with mild to moderate kidney disease. Consult your doctor before taking it.
Liver
Consult your doctorALPHACEPT M 50 TABLET is not recommended for use if you have severe liver disease. It should be used with caution in patients with mild-to-moderate liver disease. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take ALPHACEPT M 50 TABLET if you are allergic to Mirabegron, Silodosin or any of the other ingredients of this medicine.
Heart Disease
Consult your doctorALPHACEPT M 50 TABLET is not recommended for use if you have severe, uncontrolled high blood pressure. It should be used with caution in patients with ECG abnormalities (QT prolongation). Consult your doctor before taking it.
Use In Pediatrics
ContraindicatedALPHACEPT M 50 TABLET is not recommended for use in children and adolescents under 18 years of age since there is no relevant indication for this age group. Consult your doctor before taking it.
Use In Geriatrics
Use with CautionALPHACEPT M 50 TABLET should be used with caution in elderly patients. Consult your doctor before taking it.
Others
Before taking ALPHACEPT M 50 TABLET, inform your doctor if you:
- have bladder outlet obstruction
- have prostate cancer
- are scheduled for cataract surgery
- have ever fainted or felt dizzy when suddenly standing up
Interactions
A. Drug-Drug Interactions:
- Antifungals (Ex. ketoconazole, itraconazole)
- Antibiotics (Ex. clarithromycin, erythromycin)
- Antiviral (Ex. ritonavir)
- Phosphodiesterase inhibitors (Ex. sildenafil, tadalafil)
- Cardiac glycosides (Ex. digoxin, diltiazem, verapamil)
- Anticoagulants (Ex. warfarin, dabigatran etexilate)
- Immunosuppressants (Ex. cyclosporine)
- Antipsychotic (Ex. thioridazine)
- Antiarrhythmic agents (Ex. propafenone or flecainide)
- Antidepressants (Ex. imipramine or desipramine)
- Alpha1-blockers (Ex. prazosin or doxazosin)
Overdosage:
If you or anyone else accidentally takes too much of ALPHACEPT M 50 TABLET, consult your doctor immediately. Symptoms of an overdose include abnormal blood pressure or heart rate.
Synopsis
| Drug | : | Mirabegron and Silodosin |
| Pharmacological Category | : | Beta-3 Adrenergic agonist, Alpha Blockers |
| Therapeutic Indication | : | Used to Benign Prostatic Hyperplasia complicated by an overactive bladder |
| Dosage Forms | : | Tablet |
More Information
Storage
- Keep ALPHACEPT M 50 TABLET out of the reach of children
- Store below 30°C
FAQs About ALPHACEPT M 50 TABLET
Q: What if I forget to take ALPHACEPT M 50 TABLET?
A: If you forget to take ALPHACEPT M 50 TABLET, take it as soon as you remember, unless more than 12 hours have passed since the missed dose. If more than 12 hours have passed, the missed dose can be skipped, and the next dose should be taken at the usual time.
Q: What are the side effects of taking ALPHACEPT M 50 TABLET?
A: The most common side effects of taking ALPHACEPT M 50 TABLET are abnormal ejaculation, increased heart rate, urinary tract infections, dizziness, including dizziness when standing up, runny or blocked nose, constipation, and nausea. Consult your doctor if any of the side effects worsen.
Q: What is the use of the ALPHACEPT M 50 TABLET?
A: ALPHACEPT M 50 TABLET is used in the management of Benign Prostatic Hyperplasia complicated by an overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency.
Q: How does the ALPHACEPT M 50 TABLET work?
A: Mirabegron is a beta-3 adrenergic agonist that works by relaxing the muscles around the bladder. This increases the amount of urine that your bladder can hold and manages urgent, frequent, and uncontrolled urination. Silodosin is an alpha blocker that works by relaxing the muscles of the lower urinary tract and helps relieve symptoms of difficulty urinating, painful urination, urinary frequency, and urgency.
Q: Is ALPHACEPT M 50 TABLET safe during pregnancy?
A: ALPHACEPT M 50 TABLET is not recommended for use in pregnant women.
Q: Can ALPHACEPT M 50 TABLET be used in children?
A: ALPHACEPT M 50 TABLET is not recommended for use in children and adolescents under 18 years of age since there is no relevant indication for this age group.
Q: What precautions must be taken while taking ALPHACEPT M 50 TABLET?
A: Before taking ALPHACEPT M 50 TABLET, inform your doctor if you have bladder outlet obstruction, prostate cancer, are scheduled for cataract surgery, or have ever fainted or felt dizzy when suddenly standing up.
Q: How do I purchase the ALPHACEPT M 50 TABLET online?
A: If you wish to buy ALPHACEPT M 50 TABLET on Netmeds, you need a prescription from a registered medical practitioner. Netmeds has made buying online medicines more easy for consumers and is one of India's leading online pharmacies.
Q: Who should not take ALPHACEPT M 50 TABLET?
A: ALPHACEPT M 50 TABLET is not recommended for use if you have severe kidney disease, severe liver disease, or severe uncontrolled high blood pressure. Consult your doctor before taking it.
References
1. KD. Tripathi. Drugs Acting on ANS. Essentials of Medical Pharmacology. Eighth edition. 2019. Page-139.
2. Khumukcham Somarendra, and Dr. Bijit Lodh. Efficacy of mirabegron add-on therapy to silodosin for the treatment of persistent storage symptoms in patients with benign prostatic hyperplasia. Journal of Population Therapeutics and Clinical Pharmacology. February 2024. [Accessed on 2nd May 2024] https://jptcp.com/index.php/jptcp/article/view/4523
3. Windlas Biotech Limited. Mirabegron and Silodosin. [Revised in November 2023] [Accessed on 2nd May 2024] https://www.msnlabs.com/img/RxList/MFLL0042-00.pdf
4. NHS. Mirabegron. [Accessed on 2nd May 2024] https://www.nhs.uk/medicines/mirabegron/common-questions-about-mirabegron/#:
5. Medline Plus. Mirabegron. [Accessed on 2nd May 2024] https://medlineplus.gov/druginfo/meds/a612038.html
6. Medline Plus. Silodosin. [Accessed on 2nd May 2024] https://medlineplus.gov/druginfo/meds/a609002.html
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Cardiac Risk Profile
- Prostate Specific Antigen-Psa (Total)
- Prostate Specific Antigen-Psa (Free)
- Healthians Prostate Cancer Package
- Liver Function Test (LFT)
Author Details
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