Alphacept D8 Combipack Capsule 10'S

10 Capsule(s) in a Strip Mkt: Lupin Ltd Country of Origin: India
MRP ₹452.90
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Alphacept D8 Combipack Capsule 10'S ₹371.38
MRP ₹452.90
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Introduction About ALPHACEPT D8 COMBIPACK CAPSULE

ALPHACEPT D8 COMBIPACK CAPSULE is a combination of Silodosin + Dutasteride formulated to provide effective relief from urinary symptoms caused by an enlarged prostate (Benign Prostatic Hyperplasia). It helps alleviate signs like frequent urination, especially at night (nocturia), a weak or interrupted urine flow, difficulty starting urination, and a feeling of incomplete bladder emptying.

Take ALPHACEPT D8 COMBIPACK CAPSULE at the same time every day, swallowing it whole without breaking, chewing, or crushing it. Your doctor will determine the appropriate dosage for you. To maximize its effectiveness, take it consistently and avoid missing doses, even if you feel better. It may take up to 4 weeks to notice significant symptom relief. If your symptoms do not improve or worsen, inform your doctor.

This medication is not suitable for women or children. Before taking ALPHACEPT D8 COMBIPACK CAPSULE, inform your doctor if you have low blood pressure, or liver or kidney conditions, as it may not be appropriate for you. Additionally, it can interact with other medications, so ensure your doctor is aware of all medicines you are taking.

You may be advised to use condoms during sexual activity and to monitor your blood pressure regularly. Speak with your healthcare provider if you consume alcohol, as it could affect how this medicine works.

Men taking ALPHACEPT D8 COMBIPACK CAPSULE should not donate blood for at least 6 months after their last dose, in order to manage the exposure of the medicine to pregnant women via blood transfusion. Avoid consumption of alcohol while taking ALPHACEPT D8 COMBIPACK CAPSULE, as it may lower your blood pressure.

The most common side effects of this medicine include reduced libido, difficulty achieving an erection (impotence), breast tenderness, and breast enlargement.

Dizziness and drowsiness may also occur, especially when starting the treatment. If these side effects persist or bother you, consult your doctor for guidance. Remember, the benefits of this medicine are considered to outweigh the risks of potential side effects.

How to use ALPHACEPT D8 COMBIPACK CAPSULE

Dosage and Administration:

  • Initial Dosage: One dose per day, as directed by your physician.
  • Adjustments: Dosage adjustments should only be made under a doctor's supervision based on your condition and response to treatment.
  • Duration: Follow your healthcare provider’s recommendation for how long you should take ALPHACEPT D8 COMBIPACK CAPSULE.

Missed Dosage Instructions for ALPHACEPT D8 COMBIPACK CAPSULE:

  • If you forgot a dose of ALPHACEPT D8 COMBIPACK CAPSULE, take it as soon as you remember, unless it is almost time for the next dose.
  • Do not take two doses at once to make up for a missed dose.

Overdosage instructions for ALPHACEPT D8 COMBIPACK CAPSULE:

  • In case of an overdose, contact your doctor or seek emergency medical attention immediately.
  • Symptoms of overdose may include dizziness, fainting, and abnormal heartbeats.
  • Treatment of overdose may involve supportive care depending on the severity of the symptoms.

Misuse, Drug Abuse, and Dependence:

  • ALPHACEPT D8 COMBIPACK CAPSULE is not intended for misuse or abuse. It is a prescription medication that should only be used as directed by your healthcare provider.
  • There is no known risk of physical dependence or addiction with ALPHACEPT D8 COMBIPACK CAPSULE, but misuse can lead to ineffective results or side effects.

Warning & Precautions

Safety Advice

Expert Advice to Maximize the Effects of ALPHACEPT D8 COMBIPACK CAPSULE:

  • Follow Your Doctor’s Instructions: Take ALPHACEPT D8 COMBIPACK CAPSULE exactly as prescribed. Do not change your dose or stop the medication without consulting your doctor, even if you feel better, to ensure consistent results and prevent symptom recurrence.
  • Establish a Routine: Take the medicine at the same time every day to maintain consistency. Skipping doses can reduce effectiveness and delay symptom improvement.
  • Take with a Light Meal: For better absorption, take ALPHACEPT D8 COMBIPACK CAPSULE with a light meal. Avoid high-fat meals as they may increase drug levels and the risk of side effects.
  • Monitor Blood Pressure: Silodosin may cause dizziness or low blood pressure, especially at the start of treatment. Regularly check your blood pressure, particularly if you take antihypertensive medications. Consult your doctor if you feel faint or dizzy.
  • Stay Hydrated: Drink plenty of water to help prevent urinary discomfort and manage BPH symptoms.
  • Limit Alcohol: Alcohol can increase the risk of side effects like dizziness and drowsiness when combined with ALPHACEPT D8 COMBIPACK CAPSULE. Limit or avoid alcohol during treatment.
  • Avoid Grapefruit: Grapefruit and its juice can interfere with the medication's metabolism, increasing the risk of side effects. Avoid grapefruit while taking ALPHACEPT D8 COMBIPACK CAPSULE.
  • Regular Check-ups: Keep regular appointments with your doctor to track progress and adjust treatment as needed. It may take several weeks to see significant symptom relief.
  • Inform Your Doctor About Other Medications: Always inform your doctor about any other medications, including over-the-counter drugs and supplements, to avoid drug interactions that may affect the effectiveness or increase the risk of side effects.

Interactions

Drug-Drug interactions:

  1. Alpha-blockers: When ALPHACEPT D8 COMBIPACK CAPSULE is taken with other alpha-blockers (e.g., Tamsulosin), the risk of low blood pressure (hypotension), dizziness, and fainting increases. Combining these medications may lead to a stronger reduction in blood pressure.
  2. CYP3A4 Inhibitors: Drugs such as Ketoconazole, Itraconazole, and certain antifungal medications can increase Silodosin levels in the body, potentially leading to an increased risk of side effects like dizziness, drowsiness, and low blood pressure.
  3. CYP3A4 Inducers: Drugs like Rifampin, Carbamazepine, and certain anticonvulsants can reduce the effectiveness of Silodosin by increasing its metabolism, decreasing its therapeutic effects.
  4. Prostate Cancer Medications: Combining ALPHACEPT D8 COMBIPACK CAPSULE with other medications used to treat prostate cancer, such as Finasteride, may cause an overlap in their effects, leading to increased risks of side effects or complications related to prostate gland activity.
  5. Antihypertensives: Combining ALPHACEPT D8 COMBIPACK CAPSULE with blood pressure-lowering medications (e.g., ACE inhibitors, Beta-blockers) may lead to an excessive drop in blood pressure, resulting in dizziness, lightheadedness, and fainting, particularly when standing up.

Drug-Food Interactions

  1. Grapefruit: Grapefruit and grapefruit juice can affect the metabolism of Silodosin, increasing its levels in the bloodstream. This can heighten the risk of side effects like dizziness, fatigue, and hypotension. It’s best to avoid grapefruit products while taking ALPHACEPT D8 COMBIPACK CAPSULE.
  2. Fatty Foods: Consuming high-fat meals with ALPHACEPT D8 COMBIPACK CAPSULE may increase the absorption of Silodosin, leading to higher levels of the drug in the body and a greater likelihood of side effects. It’s advisable to take this medication with a light meal.
  3. Alcohol: Alcohol can increase the risk of side effects like dizziness, drowsiness, and low blood pressure when combined with ALPHACEPT D8 COMBIPACK CAPSULE. It’s recommended to limit alcohol intake while on this medication.

Synopsis

Drug :   Silodosin and Dutasteride
Pharmacological Category :   Alpha-blockers and 5-alpha-reductase inhibitor                               
Therapeutic Indication :   Benign prostatic hyperplasia      
Dosage Forms :   Tablet, Capsule

FAQs About ALPHACEPT D8 COMBIPACK CAPSULE

Q: What is ALPHACEPT D8 COMBIPACK CAPSULE used for?

A: ALPHACEPT D8 COMBIPACK CAPSULE is primarily used for managing benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate. It combines silodosin (an alpha-blocker) and Dutasteride (a 5-alpha reductase inhibitor) to reduce prostate size and improve urinary flow, alleviating BPH symptoms like frequent urination and difficulty in urination.

Q: What are ALPHACEPT D8 COMBIPACK CAPSULE benefits for prostate enlargement?

A: ALPHACEPT D8 COMBIPACK CAPSULE helps reduce the size of an enlarged prostate, improving urinary symptoms associated with benign prostatic hyperplasia (BPH). It works by relaxing the muscles around the prostate and bladder and inhibiting the hormone responsible for prostate growth. This results in better urine flow, reduced urgency, and fewer nighttime bathroom visits.

Q: How does ALPHACEPT D8 COMBIPACK CAPSULE work for BPH?

A: ALPHACEPT D8 COMBIPACK CAPSULE works by combining two active ingredients: Dutasteride+Silodosin. Silodosin relaxes the muscles in the prostate and bladder, making it easier to urinate, while Dutasteride inhibits the enzyme that converts testosterone into dihydrotestosterone, the hormone responsible for prostate growth. Together, these actions relieve BPH symptoms and reduce the size of the prostate.

Q: What are the side effects of ALPHACEPT D8 COMBIPACK CAPSULE?

A: Common side effects of ALPHACEPT D8 COMBIPACK CAPSULE include dizziness, especially when standing up quickly, fatigue, headaches, decreased libido, and sexual side effects like difficulty with ejaculation. Some men may also experience breast tenderness or enlargement due to Dutasteride. Serious side effects like allergic reactions or priapism (prolonged erection) are rare but require immediate medical attention.

Q: Is ALPHACEPT D8 COMBIPACK CAPSULE effective for BPH symptoms?

A: Yes. ALPHACEPT D8 COMBIPACK CAPSULE is highly effective in manging BPH symptoms. It reduces prostate size and improves urinary flow, helping with common symptoms like frequent urination, urgency, and difficulty starting urination. The combination of Tamsulosin and Dutasteride offers a dual-action approach for managing benign prostatic hyperplasia (BPH).

Q: Can ALPHACEPT D8 COMBIPACK CAPSULE cause sexual side effects and libido?

A: ALPHACEPT D8 COMBIPACK CAPSULE may cause sexual side effects, including a reduction in libido (sexual desire) and changes in ejaculation, such as reduced semen volume. These side effects are primarily associated with Dutasteride, but they tend to improve over time or upon discontinuation of the medication.

Q: What happens if you forgot a dose of ALPHACEPT D8 COMBIPACK CAPSULE?

A: If you forget a dose of ALPHACEPT D8 COMBIPACK CAPSULE, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not take two doses at once to make up for a missed dose, as this can increase the risk of side effects.

Q: Can ALPHACEPT D8 COMBIPACK CAPSULE cause dizziness or fatigue?

A: Yes, ALPHACEPT D8 COMBIPACK CAPSULE may cause dizziness and fatigue, especially when standing up quickly due to the effects of silodosin on blood pressure. To minimize dizziness, it is advised to rise slowly from a sitting or lying position. If fatigue or dizziness persists, consult your healthcare provider for adjustments.

Q: Can ALPHACEPT D8 COMBIPACK CAPSULE be used for long-term?

A: ALPHACEPT D8 COMBIPACK CAPSULE is generally considered safe for long-term use, especially for managing benign prostatic hyperplasia (BPH). However, it is important to have regular check-ups with your healthcare provider to monitor your response to the medication and adjust the dosage if necessary.

Q: Is ALPHACEPT D8 COMBIPACK CAPSULE safe for older adults?

A: ALPHACEPT D8 COMBIPACK CAPSULE can be used by older adults, but they may be more sensitive to the effects of the medication, particularly dizziness or fatigue. It is essential for older patients to start with the lowest effective dose and regularly monitor for any side effects. Always consult with a healthcare provider for appropriate adjustments.

Q: ALPHACEPT D8 COMBIPACK CAPSULE vs Finasteride: Which is better for BPH?

A: Both ALPHACEPT D8 COMBIPACK CAPSULE and Finasteride are used for managing BPH, but ALPHACEPT D8 COMBIPACK CAPSULE combines two medications: silodosin (for muscle relaxation) and Dutasteride (for inhibiting prostate growth). Finasteride is a single-drug therapy that also targets DHT. ALPHACEPT D8 COMBIPACK CAPSULE may provide faster symptom relief by combining both mechanisms. Your healthcare provider can recommend the best treatment based on individual needs.

Q: Can ALPHACEPT D8 COMBIPACK CAPSULE help with prostate cancer prevention?

A: ALPHACEPT D8 COMBIPACK CAPSULE is not intended for prostate cancer prevention. While Dutasteride may reduce the risk of developing prostate cancer by lowering DHT levels, ALPHACEPT D8 COMBIPACK CAPSULE is primarily used to manage benign prostatic hyperplasia. Always consult your healthcare provider about cancer prevention strategies and treatments.

Q: Can ALPHACEPT D8 COMBIPACK CAPSULE cause infertility?

A: ALPHACEPT D8 COMBIPACK CAPSULE can cause sexual impotence, decreased sex drive, or difficulty in ejaculation in men because it reduces the sperm count, semen volume, and sperm movement. Consult your doctor if this bothers you.

Author Details

Written By Srilekha. R - B.Pharm
Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile
Last updated on 13 Dec 2024 | 10:57 AM(IST)

VIDEOS

Dutasteride+Silodosin CAPSULE - Drug Information

Dutasteride+Silodosin CAPSULE : Therapeutic Uses, Warning and Precautions, Interactions, Directions for Use, Side Effects and Storage

    Net Qty
    1 N
    Shelf Life
    720
    Item Weight
    35 g
    Ingredient
    Dutasteride 0.5 mg+Silodosin 8 mg
    Hsn Code
    30049099
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