Alfacalcijoint Capsule 10'S
Introduction About ALFACALCIJOINT CAPSULE
ALFACALCIJOINT CAPSULE is a combination of Alfacalcidol and Calcium carbonate, which belongs to the group of medicines called dietary supplements. It is used in neonates, children, and adults to manage osteodystrophy (bone pain, joint pain, bone deformation, and fractures due to kidney disease or disturbances in calcium and phosphorus levels). ALFACALCIJOINT CAPSULE is also used to manage disorders of the parathyroid glands (small glands found in your neck) that may increase or decrease the calcium in your blood (hyperparathyroidism), low levels of blood calcium in newborn babies, rickets or osteomalacia (softening and weakening of bones in children and adults due to a lack of adequate vitamin D), osteoporosis (bones become weak and brittle as we age, primarily in women), and osteopenia.
While taking ALFACALCIJOINT CAPSULE, avoid foods rich in oxalic acid (ex. spinach and rhubarb), phosphate (ex. bran), or phytic acid (ex. whole cereals) for two hours. ALFACALCIJOINT CAPSULE is not recommended for use in patients with hypercalcaemia, metastatic calcification, hyperphosphatemia (except when occurring with hypoparathyroidism), or hypermagnesemia.
ALFACALCIJOINT CAPSULE should be used with caution in patients with kidney problems, including kidney stones. ALFACALCIJOINT CAPSULE should be used with caution in pregnant women, breastfeeding women, mothers of premature babies, children, adolescents, and elderly patients. The common side effects of ALFACALCIJOINT CAPSULE are diarrhea, constipation, stomach upset, abdominal pain, skin rash, and itching. If any of these become worse, contact your doctor.
Uses Of ALFACALCIJOINT CAPSULE
It is used to manage the following diseases where the amount of calcium in the body needs changing in adults, children, and neonates:
- Osteodystrophy
- Hypoparathyroidism or hyperparathyroidism
- Hypocalcaemia
- Rickets or osteomalacia
- Osteoporosis
How ALFACALCIJOINT CAPSULE Works
ALFACALCIJOINT CAPSULE regulates blood calcium levels in the body, where Alfacalcidol converts into a vitamin D metabolite to stimulate intestinal calcium absorption, increase urinary calcium excretion, and suppress parathyroid hormone (PTH) secretion, and calcium carbonate acts as a nutritional supplement to directly increase the body's calcium stores. All these actions together will increase the levels of calcium and phosphate in your body, which is useful in managing bone disorders and disturbances in the parathyroid glands.
How to use ALFACALCIJOINT CAPSULE
Take ALFACALCIJOINT CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. The correct dose and duration for you will be decided by your doctor, depending on your age, body weight, and disease condition.
Side Effects Of ALFACALCIJOINT CAPSULE
Common
- Diarrhea
- Constipation
- Stomach upset and abdominal pain
- Rash and itching
Uncommon
- Headache
- Nausea and vomiting
- Pain in the muscles
- Tiredness
- Deposits of calcium in the body
- Feeling weak or unwell
Rare
- Dizziness
Stop taking ALFACALCIJOINT CAPSULE and contact your doctor immediately if you experience any of the following side effects:
- Signs of an allergic reaction (severe skin rash, swelling of the face or throat, breathing difficulty)
- Signs of excess calcium or phosphate in your blood (feeling weak or having pain in your muscles or bones, passing urine more often, feeling thirsty, fatigue, sick, vomiting, constipation, or having lost your appetite, increased sweating, headache, confusion, and drowsiness)
- Signs of kidney problems (need to pass urine less often, swelling of any parts of your body, fever with a pain or sharp spasm in one side of your lower back)
How To Manage Side Effects
Constipation
Consume more fiber-rich foods, such as fresh fruits, vegetables, and cereals, in your diet, and drink plenty of water. Exercise more regularly. If there is no improvement, consult your doctor.
Diarrhea
Drink more fluids, such as water, fruit juice, or coconut water, to keep yourself hydrated. If there is no improvement, consult your doctor.
Stomach Pain
Take a rest to relax. Try to eat and drink slowly or have smaller and more frequent meals. Place a heating pad on your stomach. If there is no improvement, consult your doctor.
Warning & Precautions
Pregnancy
Use with CautionALFACALCIJOINT CAPSULE should be used with caution by pregnant women or women planning to have a baby. Therefore, consult your doctor for advice.
Breastfeeding
Use with CautionALFACALCIJOINT CAPSULE should be used with caution in breastfeeding women as it may pass through the breast milk. Therefore, consult your doctor for advice.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel dizzy after taking ALFACALCIJOINT CAPSULE.
Kidney
Use with CautionALFACALCIJOINT CAPSULE should be used cautiously in patients with kidney problems, including kidney stones. Consult your doctor for advice.
Allergy
ContraindicatedDo not take ALFACALCIJOINT CAPSULE if you are allergic to alfacalcidol or calcium carbonate.
Use In Pediatrics
Use with CautionALFACALCIJOINT CAPSULE should be used with caution with premature babies, newborns, children, and adolescents. Consult your doctor for advice.
Use In Geriatrics
Use with CautionALFACALCIJOINT CAPSULE should be used with caution with elderly patients. Consult your doctor for advice.
Others
ALFACALCIJOINT CAPSULE is not recommended for use if you:
- Have hypercalcaemia (high levels of calcium in your blood)
- Have metastatic calcification (high levels of calcium in your body tissues)
- Have hyperphosphatemia (except when it occurs with hypoparathyroidism)
- Have hypermagnesemia
Before taking ALFACALCIJOINT CAPSULE, inform your doctor if you:
- Have granulomas or sarcoidosis
Interactions
A. Drug-Drug interactions:
Before taking ALFACALCIJOINT CAPSULE, inform your doctor if you are taking any of the following medicines:
- Medicines used to clear fluid from the body (Ex. chlorothiazide, chlorthalidone, hydrochlorothiazide, indapamide, and metolazone)
- Medicines used to manage epilepsy (Ex. carbamazepine, phenobarbital, phenytoin, and primidone)
- Rifampicin and isoniazid (medicines used to manage tuberculosis)
- Medicines used to suppress the immune system (Ex. cortisone, prednisone, and prednisolone)
B. Drug-Food interaction:
Avoid taking ALFACALCIJOINT CAPSULE within 2 hours of eating foods rich in oxalic acid (Ex. spinach and rhubarb), phosphate (Ex. bran), or phytic acid (Ex. whole cereals).
Overdosage:
If you or anyone else accidentally takes too much of ALFACALCIJOINT CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms of an overdose are nausea or vomiting, loss of appetite, mental or mood changes, headache, weakness, and dizziness.
Synopsis
| Drug | : | Alfacalcidiol, Calcium Carbonate |
| Pharmacological Category | : | Vitamin D analogues, Minerals |
| Therapeutic Indication | : | Osteodystrophy, hypoparathyroidism or hyperparathyroidism, hypocalceamia, rickets or osteomalacia, osteoporosis |
| Dosage Forms | : | Tablet, Capsule |
More Information
Storage
- Keep ALFACALCIJOINT CAPSULE out of reach of children
- Store at room temperature
FAQs About ALFACALCIJOINT CAPSULE
Q: What is the use of ALFACALCIJOINT CAPSULE?
A: ALFACALCIJOINT CAPSULE is used in the management of hypocalcaemia, rickets or osteomalacia, hypophosphatemia, hypoparathyroidism, osteodystrophy, and osteoporosis to increase blood calcium. It also maintains the balance of calcium and phosphate metabolism in the body.
Q: Does ALFACALCIJOINT CAPSULE have vitamin D?
A: Yes, ALFACALCIJOINT CAPSULE contains Alphacalcidiol, which is similar to fat-soluble vitamin D but produced artificially. It helps increase intestinal absorption of calcium and acts as a regulator of calcium and phosphate metabolism.
Q: What are the side effects of ALFACALCIJOINT CAPSULE?
A: ALFACALCIJOINT CAPSULE may cause constipation, nausea, loss of appetite, feeling thirsty, bone pain, stomach pain, frequent urination, and muscle weakness due to its effect on the blood calcium level. If any of these symptoms bother you, consult your doctor immediately.
Q: Is ALFACALCIJOINT CAPSULE good for health?
A: ALFACALCIJOINT CAPSULE contains vitamin D and calcium, which help strengthen bones and improve the overall quality of bones. Calcium is also required for the optimal functioning of muscles, the nervous system, and the heart. Hence, taking this medicine is good for your overall health.
Q: How do I take ALFACALCIJOINT CAPSULE?
A: Always take ALFACALCIJOINT CAPSULE as instructed by your doctor and continue to follow any advice about diet recommended by your doctor. Do not stop taking the medicine suddenly because the symptoms may return.
References
1. KD Tripathi. Drugs affecting calcium balance. Essentials of medical pharmacology. Eighth edition. 2019. Page – 361, 362, 368.
2. Thawee Songpatanasilp, La-Or Chailurkit, Akekachai Nichachotsalid, Manoj Chantarasorn. Combination of alfacalcidol with calcium can improve quadriceps muscle strength in elderly ambulatory Thai women who have hypovitaminosis D: a randomized controlled trial. Journal of the Medical Association of Thailand. [Revised in September 2009] [Accessed on 31st January 2024] https://pubmed.ncbi.nlm.nih.gov/19894330/
3. LEO Pharma. Electronic Medicines Compendium (EMC). [Revised in February 2022] [Accessed on 31st January 2024] https://www.medicines.org.uk/emc/files/pil.12653.pdf
4. Biokirch GmbH. Electronic Medicines Compendium (EMC). [Revised in August 2016] [Accessed on 31st January 2024] https://www.medicines.org.uk/emc/files/pil.1295.pdf
5. CYNO Pharmaceuticals. Cecal -Plus. [Accessed on 31st January 2024] https://www.cyno.co.in/cecal-plus/#:~:text=Calcium%20carbonate%20uses%20to%20reduces,in%20digestion%20and%20upset%20stomach
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