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Quality Checked ProductsIntroduction About ADDTREX 50 TABLET
ADDTREX 50 TABLET contains Naltrexone, which belongs to the group of medicines called Opiate antagonists. ADDTREX 50 TABLET is used as a part of a management program to help affected individuals avoid taking opiates (substances that provide relief from pain) and manage them from developing opioid dependence and addiction.
ADDTREX 50 TABLET is not recommended for use in patients allergic to Naltrexone hydrochloride. It is also not recommended for use in patients who have opioid addiction (without successful withdrawal) and/or experience acute symptoms of opioid withdrawal (such as paranoia, confusion, tremors, and disorientation). The medicine is also not recommended for use in patients suffering from severe liver or kidney problems and/or acute hepatitis (inflammation of the liver).
Before taking ADDTREX 50 TABLET, inform your doctor if you have intolerance to certain sugars, such as lactose.
ADDTREX 50 TABLET should be used with caution during pregnancy and by women planning for pregnancy only if it is clearly necessary. It is not recommended for use by breastfeeding women.
The medicine is also not recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 65 years or older) after consulting the doctor.
The most common side effects of taking ADDTREX 50 TABLET are anxiety, nervousness, dizziness, abdominal pain, nausea, vomiting, diarrhea, and/or constipation. Consult your doctor if any of these symptoms worsen.
Uses Of ADDTREX 50 TABLET
- To manage opioid dependence and addiction
- Aids in the management program to help affected individuals avoid taking opiates (substances that provide relief from pain)
How ADDTREX 50 TABLET Works
ADDTREX 50 TABLET works by binding to opioid receptors, which leads to reduced opioid cravings and a blockade of the euphoric and sedative effects of opiates, thus aiding the affected individuals in overcoming opioid dependence and addiction.
How to use ADDTREX 50 TABLET
Take ADDTREX 50 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Side Effects Of ADDTREX 50 TABLET
Common
- anxiety, nervousness, irritability, affective disorders
- sleeplessness, dizziness, restlessness, and weakness
- decreased appetite, abdominal pain, nausea, vomiting, diarrhea, and constipation
- joint pain, muscle pain
- headache
- heart palpitations (racing heartbeat), increased heart rate
- libido (sexual drive) disorders, delayed ejaculation, erectile dysfunction
- thirst
- increased tear secretion/sweating
Uncommon
- oral herpes (viral infection of the lips, mouth, and gums)
- athlete’s foot (fungal skin infection)
- enlarged lymph nodes
- hallucinations, confusion, depression, paranoia, disorientation, nightmares, agitation, and abnormal dreams
- shaking, drowsiness
- vision disorders, irritation or swelling of the eye, photophobia, eye pain or strain
- changes in blood pressure
- hot flushes
- nasal congestion or discomfort, increased sputum, runny nose, sneezing,
- disorders of the mouth and throat, mouth dryness, sinus disorders, and voice disorders
- coughing, breathlessness, and yawning
- flatulence
- hemorrhoids
- ulcer
- hepatic disorders, hepatitis (inflammation of liver)
- seborrhea (a common skin problem), acne, hair loss, and itching
- groin pain
- abnormally frequent urination, painful urination
- tinnitus (ringing in the ear), vertigo (internal spinning sensation)
- ear pain/discomfort
- increased appetite, weight loss, or gain
- fever, pain, sensation of cold in extremities
Rare
- suicidal thoughts
Stop taking ADDTREX 50 TABLET and contact your doctor immediately if you experience any of the following side effects:
- feeling depressed or having suicidal thoughts or hallucinations
How To Manage Side Effects
Constipation
Try to eat high-fiber foods such as vegetables, cereals, and fresh fruit, and drink plenty of water. Involve yourself in regular exercise (going for a daily walk or run), and if this does not help, consult and inform your doctor about receiving alternate managements for constipation.
Diarrhea
Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult and inform your doctor if the symptoms worsen.
Dizziness Or Drowsiness
Try to rest and get enough sleep. Try to avoid driving or operating any tools or machines while you feel dizzy. Limit your consumption of alcohol, as it can aggravate dizziness. Consult and inform your doctor if the symptom worsens.
Headache
If ADDTREX 50 TABLET causes headaches, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking ADDTREX 50 TABLET. If it lasts more than a week or becomes severe, then consult and inform your doctor.
Nausea And Vomiting
Take ADDTREX 50 TABLET with or just after a meal. Stick to simple meals. Avoid eating oil-rich or spicy foods, sugary snacks, and drinks. Avoid drinking too much liquid along with your meals, and drink slowly in between meals. Consult your doctor if the condition worsens.
Skin rash Or Itching
Do not scratch the affected area. Wear protective clothing while going outdoors. Regularly moisturize your skin. Consult and inform your doctor if the symptom gets worse.
Thirst
Try to drink plenty of cold water, sip on cold, unsweetened drinks, and use lip balm if your lips are dry. Brush your teeth twice a day and use mouthwash. Consult and inform your doctor if the symptom gets worse.
Warning & Precautions
Pregnancy
Monitoring requiredADDTREX 50 TABLET should be used with caution during pregnancy and by women planning for pregnancy only if it is clearly necessary. Consult your doctor before taking the medicine.
Breastfeeding
ContraindicatedADDTREX 50 TABLET is not recommended for use by breastfeeding women. Consult your doctor before taking the medicine.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel less alert or drowsy after taking ADDTREX 50 TABLET.
Kidney
ContraindicatedADDTREX 50 TABLET is not recommended for use in patients with severe kidney problems. Consult your doctor before taking the medicine.
Liver
ContraindicatedADDTREX 50 TABLET is not recommended for use in patients with severe liver problems or acute hepatitis (inflammation of the liver). Consult your doctor before taking the medicine.
Allergy
ContraindicatedDo not take ADDTREX 50 TABLET if you are allergic to Naltrexone hydrochloride and/or any other ingredients of this medicine.
Use In Pediatrics
ContraindicatedADDTREX 50 TABLET is not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before taking ADDTREX 50 TABLET.
Use In Geriatrics
Use with CautionADDTREX 50 TABLET should be used with caution in elderly patients (aged 65 years or older). Consult your doctor before taking ADDTREX 50 TABLET.
Others
ADDTREX 50 TABLET is not recommended for use if you:
- are opioid-addicted (without successful withdrawal)
- experience acute symptoms of opioid withdrawal such as paranoia, confusion, tremors, and disorientation
- experience withdrawal symptoms after use of the medicine.
Before taking ADDTREX 50 TABLET, inform your doctor if you:
- intolerant to certain sugars (such as lactose)
Interactions
A. Drug-Drug interactions:
Before taking ADDTREX 50 TABLET, inform your doctor if you are taking any of the following medicines:
- medicines used to manage coughs (Ex. dextromethorphan, pholcodine)
- medicines used to manage diarrhea (Ex. loperamide, diphenoxylate)
- medicines used to manage pain (Ex. codeine, tramadol)
Overdosage:
If you or anyone else accidentally takes too much of ADDTREX 50 TABLET, consult your doctor immediately or visit a nearby hospital to manage overdose symptoms.
Synopsis
| Drug | : | Naltrexone |
| Pharmacological Category | : | Opiate antagonists |
| Therapeutic Indication | : | To manage opioid dependence and addiction, aids in the management programme to help affected individuals from taking opiates |
| Dosage Forms | : | Tablet |
More Information
- Keep ADDTREX 50 TABLET out of reach of children
- Store ADDTREX 50 TABLET below 25°C
FAQs About ADDTREX 50 TABLET
Q: What is ADDTREX 50 TABLET used for?
A: ADDTREX 50 TABLET is used in a management program to help affected individuals avoid taking opiates (substances that provide relief from pain) and manage them from developing opioid dependence and addiction.
Q: How does ADDTREX 50 TABLET work?
A: ADDTREX 50 TABLET works by binding to opioid receptors, which leads to reduced opioid cravings and a blockade of the euphoric and sedative effects of opiates, thus aiding the affected individuals in overcoming opioid dependence and addiction.
Q: How does ADDTREX 50 TABLET work?
A: ADDTREX 50 TABLET works by binding to opioid receptors, which leads to reduced opioid cravings and a blockade of the euphoric and sedative effects of opiates, thus aiding the affected individuals in overcoming opioid dependence and addiction.
Q: What are the common side effects of taking ADDTREX 50 TABLET?
A: The most common side effects of taking ADDTREX 50 TABLET are anxiety, nervousness, dizziness, abdominal pain, nausea, vomiting, diarrhea, and/or constipation. Consult your doctor if any of these symptoms worsen.
Q: How should ADDTREX 50 TABLET be taken?
A: Take ADDTREX 50 TABLET as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine. Your physician will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Q: Can ADDTREX 50 TABLET be used in pregnant women?
A: Yes, ADDTREX 50 TABLET can be used, but with caution during pregnancy and in women planning for pregnancy only if it is clearly necessary. Consult your doctor before taking the medicine.
References
1. KD Tripathi. Opioid Analgesics and Antagonists. Essentials of medical pharmacology. Seventh Edition. 2013. Page - 483.
2. Rajesh R Tampi, Aarti Chhatlani, Hajra Ahmad, Kripa Balaram, Joel Dey, Ricardo Escobar, Thejasvi Lingamchetty. Substance use disorders among older adults: A review of randomized controlled pharmacotherapy trials. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. September 2019. [Accessed on 21st February 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757194/
3. AOP Orphan Pharmaceuticals GmbH. Health Products Regulatory Authority (HPRA). [Revised in December 2021] [Accessed on 21st February 2024] https://www.hpra.ie/img/uploaded/swedocuments/56b21611-8aaa-4155-ad7d-8b973c42df04.pdf
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