Uses of Sitagliptin

Sitagliptin is used in adults to treat type 2 diabetes alone or along with other anti-diabetic medicines, diet, and exercise.

Therapeutic Category

Sitagliptin: Antidiabetic agents (Dipeptidyl peptidase-4 (DPP-4) inhibitor) 

How Sitagliptin works

Sitagliptin works by slowing down the inactivation of gut hormones released after eating the meals. This kind of action increases the secretion of insulin and decrease glucagon release (hormone which raises blood glucose level), resulting in an overall increase in blood glucose control.

Common side effects of Sitagliptin

• signs of low blood sugar (drowsiness, irritability, hunger, dizziness, confusion, sweating, weakness, and fast heartbeat)
• headache
• stuffy or runny nose, sore throat
• joint pain
• nausea, flatulence, vomiting

When to consult your doctor

Consult your doctor:

• Signs of pancreatitis (severe and continuous pain in the stomach area which might reach through your back with or without nausea and vomiting)
• Signs of serious allergic reaction (rash, hives, blistering or peeling of skin and swelling of the face, lips, tongue, and throat that may cause trouble breathing or difficulty in swallowing)
• Bullous pemphigoid symptoms such as skin blistering
• In case of accidental overdosage

Health Tips for Sitagliptin

• Maintain a balanced and nutritious diet. Consume entire foods such as vegetables, fruits, lean meats, and whole grains. Processed foods, sugary snacks and beverages, and foods high in saturated and trans fats should be avoided. Avoid skipping meals. It is important to eat regular meals while taking this medicine to reduce the risk of low blood glucose levels
• Regular physical activity will help you control your blood sugar levels, enhance your insulin sensitivity, and maintain a healthy weight. Aim for at least 150 minutes of moderate-intensity aerobic exercise per week, as well as strength training twice a week
• Limit your alcohol consumption or avoid it entirely. Alcohol may impair blood sugar management and interact with sitagliptin. Discuss with your doctor whether moderate alcohol consumption is appropriate for you
• Sitagliptin should be taken exactly as directed by your doctor. Follow the dosage and time recommendations. Do not skip or change dosages without first consulting your doctor
• Make regular follow-up appointments with your doctor to monitor your diabetes treatment. If required, they can modify your treatment plan and address any issues