Uses of Pyridostigmine

Pyridostigmine is used to treat myasthenia gravis and paralytic ileus (paralysis of digestive tract muscles). It can also be used to treat urinary retention after surgery (inability to urinate due to an anaesthetic or certain types of surgery). 

Therapeutic Category

Pyridostigmine: Acetylcholinesterase inhibitor

How Pyridostigmine works

Pyridostigmine works by preventing the breakdown of a chemical called acetylcholine, which is required to stimulate muscle movement by improving the communication between nerves and muscles. 

Common side effects of Pyridostigmine

• nausea, vomiting
• muscle cramps and twitching
• chest tightness, low blood pressure
• diarrhoea, stomach cramps or pains
• increased saliva
• chest tightness, low blood pressure

When to consult your doctor

Consult your doctor:

• If you experience allergic reaction (such as sudden wheeziness, trouble breathing, swelling of the eyelids, face or lips, rash or itching affecting your whole body)
• If you experience cholinergic crisis (visual disturbance, more than normal tear or phlegm production, irregular heartbeat, rash, too much sweating, shaking, sudden urgency to urinate)
• In case of accidental overdose or ingestion

Health Tips for Pyridostigmine

• Follow your doctor's instructions for taking pyridostigmine exactly. Without first consulting your doctor, never alter the dosage or stop taking the drug
• A healthy diet can promote overall wellbeing and may help you manage your disease. Ensure that you eat a range of nutrient-dense foods, such as fresh produce, whole grains, lean meats, and healthy fats
• Exercise can help keep muscles strong and enhance general wellbeing. What forms of exercise are safe and appropriate for your condition should be discussed with your doctor

• All of the medications you are taking, including over-the-counter medicines, dietary supplements, and herbal therapies, should be disclosed to your healthcare physician. Your doctor can help you decide whether any modifications are required because pyridostigmine and some drugs can interfere