Uses of Pentosan Polysulfate Sodium

Pentosan polysulphate sodium is used to treat bladder pain or discomfort in interstitial cystitis.

Therapeutic Category

Pentosan polysulphate sodium: Anticoagulants

How Pentosan Polysulfate Sodium works

Pentosan polysulphate sodium works by strengthening and modifying glycosaminoglycans (a type of complex carbohydrates present in the walls of urinary bladder) which provides relief from painful bladder filling and facilitates proper emptying of bladder thus treating symptoms of interstitial cystitis.

Common side effects of Pentosan Polysulfate Sodium

• hair loss
• diarrhoea, nausea
• headache
• rash
• indigestion, abdominal pain
• dizziness
• swelling in ankles and legs
• back pain, pelvic pain
• frequent urination
• weakness
• enlarged abdomen
• rectal haemorrhage
• symptoms of influenza such as fever or feeling feverish/chills, cough, sore throat and runny or stuffy nose

When to consult your doctor

Consult your doctor if you experience:

• signs of changes in the retina of the eye (pigmentary maculopathy) such as vision abnormalities including difficulty while reading, visual distortions and altered colour vision
• sensitivity to light
• signs of increased bleeding such as easy bruising, nosebleeds, gum bleeding or blood in stool

Health Tips for Pentosan Polysulfate Sodium

• Take the medication exactly as prescribed by your doctor. Avoid increasing or decreasing the dose without consulting your doctor
• Drinking plenty of water can help flush out toxins and reduce bladder irritation. Aim to drink at least 8 cups of water per day or as advised by your healthcare provider
• Focus on a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. A healthy diet can support overall well-being and may help reduce inflammation
• Pentosan polysulphate sodium is not recommended for use in pregnant or planning for pregnancy or breast feeding