Uses of Nortriptyline+Pregabalin

The combination of Nortriptyline and Pregabalin is indicated for the management of neuropathic pain.      

Therapeutic Category

Nortriptyline: Tricyclic antidepressants   

Pregabalin: Fibromyalgia agents    

How Nortriptyline+Pregabalin works

Nortriptyline + Pregabalin effectively relieves nerve pain, where nortriptyline acts by inhibiting the movement of pain signals from the brain by blocking the reuptake of certain chemical messengers (norepinephrine and serotonin) at the pre-synapse and pregabalin acts by interfering with influx of calcium and various pain signals travelling through the damaged nerves and the brain, thus leading to a significant pain relief in various neuropathic pain states.

Common side effects of Nortriptyline+Pregabalin

• dizziness, drowsiness, headache
• nausea or vomiting
• dry mouth
• diarrhea, constipation, swollen abdomen, flatulence
• increased appetite, weight gain
• blurred vision
• vertigo (spinning sensation)
• mania, confusion, irritability, disorientation
• insomnia (lack of sleep) or sleepiness
• decreased sex drive, erectile dysfunction
• lack of control over body movements, tremor (shaking)
• memory impairment, attention disturbance
• dysarthria (unable to speak properly)
• numbness or pain in the body
• generalized edema (swelling of the body including extremities)
• muscle cramps
• pain in the joints, back or limbs
• sore throat 

When to consult your doctor

Consult your doctor:

• In case of accidental overdosage
• If you experience swollen face or tongue
• If you experience skin redness with blisters or peeling

Health Tips for Nortriptyline+Pregabalin

• Take Nortriptyline + Pregabalin exactly as directed by your doctor. Follow the specified dosage and regimen. Do not change the dosage or discontinue the medicine without first consulting your doctor
• Avoid consumption of alcohol while taking Nortriptyline + Pregabalin as it could make you feel dizzier or sleepier
• Do not drive or operate any tools or machines if you experience impairment of mental and physical, dizziness or sleepiness after taking Nortriptyline + Pregabalin
• Nortriptyline + Pregabalin is not recommended for use in pregnant women or women of childbearing age unless considered clearly necessary and breast-feeding women
• It is not recommended for use in patients having severe liver disease, heart disease (such as recent heart attack, heart block or cardiac arrhythmias) and mania (abnormally excited mood)
• Before taking Nortriptyline + Pregabalin inform your doctor if you are taking or have recently taken prescription medicines, over the counter drugs (OTC), supplements including herbal products as it may interact with each other leading to potential decrease in therapeutic effectiveness or increase the risk of any unusual effects