Uses of Neostigmine

Neostigmine is used for the treatment of myasthenia gravis. It is also used to reverse the effects of muscle relaxants, normalise intestinal movements and treat urinary retention after surgery.

Therapeutic Category

Neostigmine: Cholinergic drugs

How Neostigmine works

Neostigmine increases muscle strength by blocking the action of an enzyme in the body which blocks nerve impulses to muscles. By stopping this enzyme from working, it strengthens muscles and thus helps in easing of intestinal movements and urinary retention.

Common side effects of Neostigmine

• Increased or decreased heart rate, low blood pressure
• Dry mouth, nausea, vomiting
• Throat pain, procedural complication or pain
• Dizziness, headache, postoperative shivering, prolonged neuromuscular blockade causing paralysis of the affected skeletal muscles
• Difficulty in sleeping
• Difficulty in breathing
• Pruritus (itchy skin)

When to consult your doctor

Consult your doctor if you experience:

• Allergic reaction (sudden wheeziness, trouble breathing, swelling of the eyelids, face or lips, rash or itching especially of your whole body)

Health Tips for Neostigmine

• Take Neostigmine as directed by your doctor. Avoid exceeding the recommended dosage, as it can lead to adverse effects
• Follow a balanced and nutritious diet that includes a variety of fruits, vegetables, whole grains, lean proteins and healthy fats
• Avoid consumption of alcohol while taking Neostigmine as it may increase its side effects
• Drink plenty of water to stay hydrated and relieve these symptoms
• Neostigmine should be used with caution in pregnant or breastfeeding women