Uses of Meropenem+Sulbactam

The combination of Meropenem + Sulbactam is used to treat serious bacterial infections of the respiratory tract (Ex. pneumonia, cystic fibrosis), urinary tract (Ex. cystitis), stomach, genital tract (Ex. postpartum infections), skin and soft tissues (Ex. abscess, cuts, wounds), brain (Ex. meningitis) and blood (Ex. sepsis).

Therapeutic Category

Meropenem: Antibiotics

Sulbactam: Antibiotics

How Meropenem+Sulbactam works

Meropenem is a powerful antibiotic. It destroys the susceptible bacteria by interfering with the bacterial cell wall synthesis. It is effective against a wide range of bacteria (including both gram-positive and gram-negative bacteria).

Sulbactam is a beta-lactamase inhibitor. It sustains the anti-bacterial activity of meropenem against the toxic bacterial proteins (such as beta lactamases). Collectively, these actions destroy the susceptible bacteria, prevent their further growth and multiplication which in turn reduces the severity of the infection.

Common side effects of Meropenem+Sulbactam

• stomach pain
• nausea, vomiting
• diarrhoea
• headache
• skin rash, itchy skin
• Injection site reactions (pain and inflammation)

When to consult your doctor

Consult your doctor if you experience:

• signs of severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat or tongue causing difficulty in breathing or swallowing)
• severe skin reactions (such as widespread skin rash, blistering, peeling or bleeding on any part of the skin with fever, chills, enlarged lymph nodes and malaise or pink or reddish skin lesions on palms or soles)
• fever, skin rash, liver problems, increase in WBC count, enlarged lymph nodes
• breathlessness, red or brown urine

Health Tips for Meropenem+Sulbactam

• Meropenem+Sulbactam should be used under careful medical supervision
• Make sure to receive therapy with Meropenem + Sulbactam for the stipulated duration as instructed by your doctor. Stopping therapy or skipping doses in between therapy may not control infection effectively
• While taking Meropenem + Sulbactam, avoid concomitant use of oral anticoagulants such as warfarin, acenocoumarin or medicines to treat fits without consulting your doctor
• Before undergoing therapy with Meropenem + Sulbactam, inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you previously experienced diarrhea after taking any antibiotics as a precaution
• Meropenem+Sulbactam is generally not recommended for use in pregnant women. Therefore, consult your doctor before taking it
• Meropenem+Sulbactam may pass through the breast milk. Therefore, it should be used in breastfeeding women only if considered necessary by the physician