Uses of Levosulpiride

Levosulpiride is used to treat nausea, vomiting, indigestion and diabetic gastroparesis. It is also used in the treatment of depression and schizophrenia in adults.

Therapeutic Category

Levosulpiride: Selective dopamine D2 receptor antagonists

How Levosulpiride works

Levosulpiride is an antipsychotic medicine with anti-emetic and anti-dyspeptic properties. It acts by blocking the actions of certain chemical messengers (dopamine and serotonin) in the brain that controls the mood, behaviour and movement of stomach muscles. As a result, it improves muscle movement in the stomach (gastric motility) and reduces the unpleasant symptoms of GI tract (such as nausea, vomiting, indigestion, sensation of fullness and lack of appetite). It can also stabilize your mood, reduces the signs of depression and control abnormal thoughts and behaviours.

Common side effects of Levosulpiride

• headache
• drowsiness, tiredness
• sedation
• weight gain
• lack of sleep
• increased salivation, tremor
• breast enlargement and discharge
• decrease in sex drive, problems in erection
• stomach pain, constipation, dry mouth, diarrhea
• restlessness, anxiety, nervousness
• tremors, muscle spasms

When to consult your doctor

Consult your doctor:

• in case of accidental overdosage
• if you experience signs of Neuroleptic malignant syndrome (such as high fever, rigid muscles, mood swings, fast or irregular heartbeat, changes in blood pressure, increased sweating)
• if you experience feeling dizzy or faint while standing up
• if you experience severe skin reactions (such as redness, blistering, peeling of skin and bleeding in the lips, eyes, mouth, nose and genitals with fever)
• if you experience chest pain, fast or irregular heartbeat, difficulty in breathing, feeling faint

Health Tips for Levosulpiride

• Avoid certain trigger foods, eating smaller meals, avoiding lying down immediately after eating, and maintain a healthy weight
• Avoid alcohol consumption while taking Levosulpiride as it can lead to drowsiness and dizziness