Uses of Hydrochlorothiazide+Losartan

The combination of Hydrochlorothiazide and Losartan is indicated for the treatment of essential hypertension.  

Therapeutic Category

Hydrochlorothiazide: Diuretics (Thiazide-type diuretic)

Losartan: Antihypertensive agents (Angiotensin receptor blockers (ARBs))

How Hydrochlorothiazide+Losartan works

Hydrochlorothiazide + Losartan reduces elevated blood pressure, where hydrochlorothiazide works by making the kidneys pass more water and salt (i.e., urine) and losartan works by inhibiting the binding of angiotensin II (a substance produced in the kidneys which causes narrowing of blood vessels) to its receptors, thus causing the blood vessels to relax which in turn decreases elevated blood pressure. 

Common side effects of Hydrochlorothiazide+Losartan

• cough
• respiratory problems (infections in upper airway, nasal congestion or sinusitis)
• diarrhea, stomach pain, nausea, indigestion
• muscle pain or cramps
• pain in legs and back
• lack of sleep (insomnia)
• headache
• dizziness
• tiredness or weakness
• chest pain
• signs of low blood sugar (dizziness, shaking, sweating, tiredness, and fast heartbeat)

When to consult your doctor

Consult your doctor:

• In case of accidental overdosage
• If you experience severe allergic reactions (such as skin rash, itching, swelling of the face, lips, mouth or throat, and difficulty in swallowing or breathing)
• If you experience bleeding or bruising, repeated infections (due to low white blood cells)
• If you experience heart problems (such as an abnormal heartbeat, cerebrovascular accident or heart attack)
• If you experience fluid accumulation in the lungs
• If you experience pancreatitis (inflammation of pancreas which results in severe pain in the back and abdomen)
• If you experience toxic epidermal necrolysis (skin rash with blisters and skin peeling)
• If you experience hepatitis (inflammation of the liver)

Health Tips for Hydrochlorothiazide+Losartan

• Reduce your intake of high-sodium items including processed foods, fast food and salty snacks. Lowering sodium intake can help reduce blood pressure
• Stay hydrated by drinking plenty of water throughout the day. Proper hydration is essential for overall health and blood pressure control. Reduce consumption of caffeinated beverages, as excessive caffeine can affect blood pressure and heart rate
• Exercise on a regular basis can help decrease blood pressure and enhance cardiovascular health. As prescribed by your doctor, aim for at least 150 minutes of moderate-intensity aerobic activity every week
• If you are overweight, decreasing weight can improve your blood pressure control substantially. A healthy weight improves general well-being
• Avoid drinking alcohol as it can affect the blood pressure and interact with your medications. If you smoke, consider quitting. Smoking has negative effects on blood pressure and heart health
• Use stress-relieving strategies such as meditation and deep breathing exercises. Stress reduction can improve blood pressure levels
• Monitor your blood pressure on a regular basis, as directed by your doctor. Keeping track of your blood pressure levels assists you and your doctor in determining the efficacy of the treatment
• Take Hydrochlorothiazide+Losartan exactly as directed by your doctor. Follow the specified dosage and regimen. Do not change the dosage or discontinue the medicine without first consulting your doctor