Uses of Glibenclamide+Metformin

The combination of Glibenclamide+Metformin is used to treat type II diabetes mellitus along with diet and exercise. 

Therapeutic Category

Glibenclamide+Metformin: Antidiabetic agents

How Glibenclamide+Metformin works

Glibenclamide reduces blood glucose levels by making the pancreas secrete more insulin (a hormone that digest glucose in the body). This helps the body to make utilise of the circulating blood glucose levels and reduces blood sugar levels. Metformin blocks the amount of glucose produced by the liver. It also reduces the absorption of glucose in the intestines and allows the body to make better use of insulin. 

Common side effects of Glibenclamide+Metformin

• diarrhoea
• headache
• nausea, vomiting
• stomach pain
• dizziness
• weight gain
• changes in taste

When to consult your doctor

Consult your doctor if you experience:

• severe allergic reactions (such as swelling of the face, lips, mouth, tongue, or throat that may lead to difficulty in breathing or swallowing)
• symptoms of lactic acidosis (such as vomiting, stomach pain, decreased heartbeat, difficulty in breathing, muscle cramps, general weakness with severe tiredness or reduced body temperature)
• signs of low blood sugar (such as headache, drowsiness, weakness, irritability, slurred speech, hunger, fast heartbeat, confusion, shaking or feeling jittery, mood changes, dizziness, sweating, blurred vision, anxiety, tingling hands)
• signs of liver problems (such as nausea or vomiting, stomach pain, unusual or unexplained tiredness, loss of appetite, dark urine, yellowing of the skin or the whites of the eyes)

Health Tips for Glibenclamide+Metformin

• Glibenclamide + Metformin should be taken preferably with meals to avoid nausea or stomach upset. Strictly follow the dosing schedule as advised by your physician to achieve better results
• Along with the therapy, follow the low sugar diet and lifestyle advice as instructed by your doctor to achieve better results. Avoid eating sweets, candies, cakes, pastries and high sugary foods
• Avoid consumption of alcohol, as it could interact with this medicine and increase the risk of side effects
• Before taking Glibenclamide + Metformin, inform your doctor if you have any heart, liver, or kidney problems. You must also inform your doctor if you have any hormonal problems or if you are severely dehydrated, malnourished, starved, on an irregular diet
• Do not take Glibenclamide + Metformin if you are pregnant or breastfeeding without consulting your doctor
• Regularly visit your doctor and take all the necessary tests which your doctor recommends to you without fail