Uses of Gentamicin

Gentamicin is used to manage various types of infections such as skin, wound and blood infections.

Therapeutic Category

Gentamicin: Antibiotics

How Gentamicin works

Gentamicin works by inhibiting the growth and multiplication of bacteria. It does this by binding to the bacterial ribosomes, which are essential for protein synthesis, and disrupting the production of bacterial proteins.

Common side effects of Gentamicin

• Local irritation, inflammation or rash
• Nausea or vomiting
• Skin rash or development of raised coloured blotches which may be itchy
• Purple discolouration under the skin
• Fever, sore throat and mouth
• Muscle weakness
• Kidney disease with symptoms such as reduced urine output
• Low blood cell counts (red and white blood cells) and further blood abnormalities or disorders (known as blood dyscrasia)
• Damage to the brain with signs such as seizures, confusion, tiredness, depression and hallucinations
• Liver problems
• Low potassium or calcium or magnesium levels in the blood
• High urine levels of phosphate and amino acids (so called Fanconi-like syndrome, associated with high doses given over a long time)

When to consult your doctor

Consult your doctor, if you experience:

• Severe allergic reaction such as sudden itchy rash (hives), swelling of the hands, feet, ankles, face, lips, mouth or throat (which may cause difficulty in swallowing or breathing), and you may feel you are going to faint

Health Tips for Gentamicin

• Take gentamicin exactly as prescribed by your healthcare provider. Do not stop taking the medication early, even if you start feeling better, unless directed by your healthcare provider
• Gentamicin can be harmful to the kidneys, so your healthcare provider will monitor your kidney function during treatment
• Stay hydrated by drinking plenty of water throughout the day
• Avoid consumption of alcohol, which can increase the risk of gentamicin-related side effects, especially on the kidneys and the nervous system
• Inform your healthcare provider of all medications and supplements you are using to check for potential drug interactions
• Before taking or using Gentamicin, consult your doctor if you are pregnant or breastfeeding women