Uses of Dapsone

Dapsone is used in the treatment of leprosy, blistering skin disorders such as dermatitis herpetiformis (which is connected to gluten sensitivity) and acne vulgaris. Also, it prevents pneumonia in immunodeficient patients (particularly in AIDS patients). 

Therapeutic Category

Dapsone: Sulfone antibiotics 

How Dapsone works

Dapsone acts as both antibacterial and antiprotozoal medicine in the same way as sulphonamides, that is by inhibiting the synthesis of di-hydro folic acid through competition with a chemical that is necessary for the growth and multiplication of the microorganisms (bacteria, protozoa). Also, it acts as an anti-bacterial and anti-inflammatory agent in the treatment of acne vulgaris which works by inhibiting the synthesis of folic acid which is necessary for the growth of bacteria. Thus, stops the multiplication of bacteria. As an anti-inflammatory agent, it decreases inflammation and heals the breakout.     

Common side effects of Dapsone

• oiliness/peeling
• redness
• dryness

When to consult your doctor

• In case of accidental overdosage
• If you experience dapsone syndrome (which may occur after three to six weeks of treatment) which causes symptoms such as skin rashes, fever and changes in blood cells (characterised by fatigue, shortness of breath, muscle weakness, fast heartbeat) may occur which may lead to severe skin reactions, liver inflammation, kidney damage and mental illness.  
• If you experience signs of methemoglobinemia (such as dizziness, breathlessness, slate grey or blueish colouring of the skin, especially in buccal mucous membranes, lips and nail beds)

Health Tips for Dapsone

• Eat a balanced diet with a variety of nutritious foods to support your overall health and well-being. Drink plenty of water to stay hydrated, which is essential for overall health
• Smoking can affect blood circulation and may impact the effectiveness of this medicine. If you smoke, consider quitting to improve treatment outcomes
• Avoid consuming alcohol while taking this medicine, as it may interact with the medication and cause adverse effects
• This medicine may increase sensitivity to sunlight. Use sunscreen with a high SPF, wear protective clothing and avoid prolonged sun exposure, especially during peak hours
• Keep the affected area clean and dry. Change clothes regularly, especially if they come into contact with the treated skin. If you experience dryness or irritation while using this medicine, consider using a non-comedogenic and hypoallergenic moisturizer to soothe the skin
• Individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency should avoid certain triggers, such as fava beans and certain medications, as this medicine may exacerbate this condition
• Take this medicine as prescribed by your doctor. Follow the dosing schedule and instructions carefully. Do not stop or change the dosage without consulting your doctor