Uses of Clozapine

Clozapine is used to treat schizophrenia and to treat psychotic disorders occurring in patients with Parkinson’s disease.

Therapeutic Category

Clozapine: Atypical antipsychotics

How Clozapine works

Clozapine works by blocking dopamine receptors (proteins responsible for synthesis and release of dopamine) in brain which results in reduced synthesis of dopamine thus improving thoughts, feelings and behaviour and thereby treating symptoms of schizophrenia and other psychotic disorders associated with Parkinson’s disease in affected individuals.

Common side effects of Clozapine

• stomach pain
• headache, dizziness
• constipation, flatulence, heartburn, indigestion, diarrhea
• mouth ulcers
• nausea, vomiting
• feeling weak or tired
• bruising

When to consult your doctor

Consult your doctor:

• In case of accidental overdosage
• If you experience severe constipation
• If you experience fast heartbeat
• If you experience signs of a cold, fever, flu-like symptoms, sore throat or any other infection
• If you experience seizures (fits)
• If you experience sudden fainting/ loss of consciousness with muscle weakness

Health Tips for Clozapine

• Drink an adequate amount of water to maintain proper hydration and to manage increased salivation or dry mouth
• Maintain a healthy diet that includes a variety of fruits, vegetables, whole grains, and lean proteins. Avoid excessive consumption of sugary or fatty foods, as Clozapine may increase the risk of weight gain and metabolic changes
• Engage in regular physical activity. It can be beneficial for both your physical and mental well-being. It can help weight, improve cardiovascular health, and reduce the risk of metabolic side effects
• Avoid smoking as it can interact with the effectiveness of the medication
• Manage stress such as practicing relaxation techniques, engaging in hobbies, or seeking support from friends, family, or support groups for overall mental health
• Get sufficient sleep