Uses of Chlorpromazine

Chlorpromazine is used in the treatment of schizophrenia and other psychoses (especially paranoid), mania and hypomania, anxiety, psychomotor agitation, excitement, violent or dangerously impulsive behaviour, intractable hiccup and nausea, vomiting of terminal illness (where other medicines have failed or are not available). It is also used to treat schizophrenia and autism (in children).

Therapeutic Category

Chlorpromazine: Antipsychotics

How Chlorpromazine works

Chlorpromazine exerts its antipsychotic effect by blocking postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby preventing the excess of dopamine in the brain.

Common side effects of Chlorpromazine

• drowsiness
• dry mouth or stuffy nose
• blurred vision
• constipation
• impotence

When to consult your doctor

Consult your doctor if you experience:

• sudden appearance of sore throat, fever or other signs of infection
• allergic reactions symptoms such as hives, difficult breathing, swelling of your face, lips, tongue, or throat
• uncontrolled muscle movements in your face such as chewing, lip smacking, frowning, tongue movement, blinking or eye movement
• stiffness in your neck, tightness in your throat, trouble breathing or swallowing
• confusion, agitation, feeling jittery, trouble sleeping
• weakness
• breast swelling or discharge
• seizures
• jaundice (yellowing of the skin or eyes)
• low white blood cell counts such as fever, chills, mouth sore, skin sore, sore throat, cough, trouble breathing, feeling light-headed
• severe nervous system reactions such as very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors

Health Tips for Chlorpromazine

• Drink an adequate amount of water daily to stay hydrated, as Chlorpromazine can cause dry mouth
• Maintain a balanced and nutritious diet to maintain a healthy weight
• Engage in regular physical activity as recommended by the doctor as it can help improve mood and overall well-being
• Chlorpromazine can increase your skin’s sensitivity to sunlight. Use sunscreen, wear protective clothing, and limit sun exposure to avoid sunburn
• Do not consume alcohol while using Chlorpromazine as it may lead to adverse effects
• Do not drive or operate any machines if you feel dizziness or drowsiness after using Chlorpromazine
• Practice stress-relief techniques such as deep breathing, meditation, or yoga to help manage your mental health
• Avoid exertion as this medication can cause fatigue, so take breaks when need and get enough rest