Uses of Carvedilol

Carvedilol is used to treat high blood pressure (Hypertension) and angina pectoris (Chest pain) and heart failure.

Therapeutic Category

Carvedilol: Beta-blockers

How Carvedilol works

Carvedilol works by blocking Beta receptors (Beta-1 and Beta- 2) and alpha1 receptors causing relaxation of blood vessels. This makes it easier for the heart to pump blood around the body and reduces blood pressure and strain on your heart. It has also a calcium channel blockade effect in high doses, antioxidant/ free radical scavenging properties.

Common side effects of Carvedilol

• lack of muscle strength, weakness, dizziness or feeling unwell, tiredness, headache
• infections of the airway Ex. bronchitis, pneumonia, asthma, nose and throat (upper respiratory tract) causing wheezing, shortness of breath, chest tightness and sore throat
• decreased red blood cells (causing pale skin, tiredness, heart palpitations and shortness of breath)
• weight gain
• increased cholesterol levels in the blood
• change in blood sugar levels
• depression or depressed mood
• dry eyes
• decreased volume of circulating blood
• fluid accumulation in the lungs
• pain in hands and feet
• stomach acidity, indigestion, stomach pain, nausea, vomiting, loose stools
• kidney problems
• urinary tract infections which can use difficulty in passing urine
• hardening of the arteries (atherosclerosis) results in worsening of symptoms in patients with Raynaud’s disease (cold hands and feet or pain in the legs which worsens when walking)

When to consult your doctor

Consult your doctor if you experience:

• an allergic reaction (swelling of the face, lips, throat and mouth, leading to breathing difficulty or swallowing; skin rash, hives
• flu-like symptoms (Ex. headache, fever, chills and body aches)
• serious skin reactions such as (erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis) can occur. Redness often associated with blisters may appear on the skin, mouth, genital areas or eyelids. These may lead to widespread peeling of the skin
• chest pain accompanied by shortness of breath, sweating and feeling sick
• decreased urination often with swelling of legs (indicates problems with kidneys)
• low blood sugar (hypoglycaemia) which may lead to seizures or unconsciousness
• In case of accidental overdosage or ingestion

Health Tips for Carvedilol

• Try to take Carvedilol at the same time each day to maintain consistent blood levels and optimize its effectiveness
• Carvedilol can interact with alcohol and other medications, leading to adverse effects or reducing its effectiveness
• Carvedilol is generally not recommended for use in pregnant and breast feeding women