Uses of Aspirin+Clopidogrel+Rosuvastatin

The combination of Aspirin+Clopidogrel+Rosuvastatin is indicated for the treatment of acute coronary syndrome, myocardial infarction (heart attack), angina (chest pain) or stroke (reduced blood supply to brain leading to brain death) that were caused due to clot or plaque formation in the blood vessels supplying the heart.

Therapeutic Category

Aspirin: Antiplatelets

Clopidogrel: Antiplatelets

Rosuvastatin: HMG-CoA reductase inhibitors

How Aspirin+Clopidogrel+Rosuvastatin works

Aspirin+Clopidogrel+Rosuvastatin effectively improves cardiac function and reduces the risk of heart problems, where clopidogrel acts by inhibiting platelet aggregation in the coronary arteries, aspirin acts by blocking the actions of an enzyme called cyclo-oxygenase 1 which is believed to be responsible for catalyzing the synthesis of platelets and rosuvastatin acts by inhibiting the action of an enzyme called HMG-CoA reductase, which is required to catalyze the formation of cholesterol, thus preventing clot or plaque formation in the coronary arteries leading to an uninterrupted supply of oxygen and blood to the heart.

Common side effects of Aspirin+Clopidogrel+Rosuvastatin

• Increased bleeding or bruising
• Indigestion, diarrhea, stomach pain, nausea, constipation
• Bleeding in the gut
• Diabetes (high blood glucose)
• Dizziness and headache
• Muscle cramps or pain
• Weakness or lack of energy
• Epistaxis (bleeding from the nose)

When to consult your doctor

Consult your doctor, if you experience:

• Severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat and neck, difficulty in breathing or swallowing)
• Thrombotic Thrombocytopenic Purpura (a blood disorder that causes blood clots in capillaries throughout the body)
• Severe skin disorders with fever (Ex. Lyell’s syndrome, Steven-Johnsons syndrome, erythema nodosum, erythema multiforme)
• Symptoms of pancreatitis (such as moderate to severe abdominal pain, nausea, vomiting, fever, rapid heart rate)
• Jaundice (yellowing of eyes, skin and urine with fever)
• Rhabdomyolysis (muscle rupture)
• Unusual bleeding (such as blood in vomit or urine, coughing up blood, black stools, purple spots under the skin)
• Flu-like symptoms (fever, cough, sore throat, headache and extreme tiredness)
• Breathing difficulties (Ex. bronchospasm, asthma attack)
• Hemorrhagic vasculitis (inflammation of the blood vessels with bleeding)
• Abnormal heavy or prolonged menstrual periods

Health Tips for Aspirin+Clopidogrel+Rosuvastatin

• Always take Aspirin+Clopidogrel+Rosuvastatin exactly as prescribed by your healthcare provider. Do not skip the dose or stop taking this medicine
• A healthy lifestyle includes eating a balanced diet, getting regular exercise, managing stress, and getting enough sleep
• Stay hydrated by drinking plenty of water throughout the day
• Avoid alcohol and quit smoking while taking Aspirin+Clopidogrel+Rosuvastatin, as it can reduce their effectiveness and may lead to more pronounced side effects
• Attend any follow-up appointments with your healthcare provider as recommended
• Inform your healthcare provider about any other medications you are taking, including over-the-counter drugs and supplements
• Aspirin+Clopidogrel+Rosuvastatin is not recommended for use in pregnant or planning for pregnancy or breast feeding women