Uses of Amphotericin B

Amphotericin B is used to treat invasive fungal infections in patients who are resistant/intolerant to conventional Amphotericin B therapy by binding to a fungal steroid named ergosterol.

Therapeutic Category

Amphotericin B: Anti fungal agents

How Amphotericin B works

Amphotericin B is an anti fungal agent that binds to ergosterol (steroid present on the cell membranes of fungi) which leads to the formation of pores and ion leakage on the cell membrane resulting in fungal cell death thus treating invasive fungal infections in affected individuals. 

Common side effects of Amphotericin B

• fever
• chills/rigors
• nausea
• vomiting
• skin reactions

When to consult your doctor

Consult your doctor:

• In case of accidental overdosage

Health Tips for Amphotericin B

• Amphotericin B is a potent medication, and the dosage and administration schedule are determined by your healthcare provider. Always adhere to their recommendations and do not change the dosage or frequency without consulting them
• Amphotericin B can stress the kidneys, so it's crucial to stay well-hydrated during treatment. Drink plenty of water unless otherwise instructed by your doctor
• Regularly monitor your kidney function with blood tests while on Amphotericin B. This helps to detect any potential kidney function-related side effects early on
• Amphotericin B can cause disturbances in electrolyte balance, such as potassium and magnesium. Your doctor may recommend supplements or adjust your diet to maintain proper electrolyte balance
• While on Amphotericin B, it's best to avoid alcohol consumption, as it can worsen the potential side effects on the liver and kidneys
• Consult your doctor if you are pregnant or breastfeeding before taking or using this medicine