Uses of Amlodipine+Indapamide

The combination of Amlodipine and Indapamide is used in the treatment of hypertension (high blood pressure).   

Therapeutic Category

Amlodipine: Antihypertensive agents (Calcium channel blocker)

Indapamide: Antihypertensive agents (Thiazide diuretics)

How Amlodipine+Indapamide works

Amlodipine+Indapamide helps to reduce high blood pressure, where amlodipine works by inhibiting the movement of calcium ions into both vascular smooth muscle and cardiac muscle, resulting in lower blood pressure by relaxing the blood vessels and improving the flow of blood to the heart muscles. Indapamide reduces blood pressure by promoting the excretion of extra fluid and certain salts (sodium) from the body by increasing the amount of urine produced by the kidneys.  

Common side effects of Amlodipine+Indapamide

• headache
• dizziness
• nausea
• stomach pain
• visual disturbances
• muscle cramps
• diarrhea
• constipation
• indigestion
• increased heart rate
• flushing (skin redness)
• weakness, tiredness
• oedema (fluid retention)
• red raised rashes on the skin

When to consult your doctor

Consult your doctor:

• In case of accidental overdosage
• If you experience severe skin reactions such as stevens-johnson syndrome, toxic epidermal necrolysis (skin rash, itching, blistering reddening of skin all over the body, peeling and swelling of the skin, swelling of the mucous membrane)
• If you experience irregular heartbeat
• If you experience signs of an inflamed pancreas (severe stomach and back pain, usually feeling unwell)
• If you experience sudden chest pain, wheezing and trouble breathing
• If you experience angioedema or urticaria (such as rash, swelling of the face, lips, mouth, throat or airways which can lead to difficulty in breathing or swallowing)

Health Tips for Amlodipine+Indapamide

• Reduce your intake of high-sodium items including processed foods, fast food and salty snacks. Lowering sodium intake can help reduce blood pressure
• Stay hydrated by drinking plenty of water throughout the day. Proper hydration is essential for overall health and blood pressure control. Reduce consumption of caffeinated beverages, as excessive caffeine can affect blood pressure and heart rate
• Exercise on a regular basis can help decrease blood pressure and enhance cardiovascular health. As prescribed by your doctor, aim for at least 150 minutes of moderate-intensity aerobic activity every week
• If you are overweight, decreasing weight can improve your blood pressure control substantially. A healthy weight improves general well-being
• Avoid drinking alcohol as it can affect the blood pressure and interact with your medications. If you smoke, consider quitting. Smoking has negative effects on blood pressure and heart health
• Use stress-relieving strategies such as meditation and deep breathing exercises. Stress reduction can improve blood pressure levels
• Monitor your blood pressure on a regular basis, as directed by your doctor. Keeping track of your blood pressure levels assists you and your doctor in determining the efficacy of the treatment
• Take Amlodipine+Indapamide exactly as directed by your doctor. Follow the specified dosage and regimen. Do not change the dosage or discontinue the medicine without first consulting your doctor