Uses of Abemaciclib

Abemaciclib is  used to manage certain types of breast tumor (hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-)).

Therapeutic Category

Abemaciclib: Bruton tyrosine kinase (BTK) inhibitors

How Abemaciclib works

Abemaciclib blocks the effects of proteins called cyclin-dependent kinase 4 and 6. These proteins are abnormally active in some tumor cells and make them grow out of control. It blocks the action of these proteins can slow down growth of tumor cells, shrink the tumour and delay progression of the tumor.

Common side effects of Abemaciclib

• Infections
• Reduction in white blood cells, red blood cells, and blood platelets
• Nausea (feeling sick), vomiting
• Inflammation or sore mouth
• Decreased appetite
• Headache
• Alteration in sense of taste
• Hair loss
• Tiredness
• Dizziness
• Itching
• Rash
• Abnormalities in liver blood tests

When to consult your doctor

Consult your doctor, if you experience:

• Diarrhea
• Symptoms such as chills or fever
• Painful swollen leg, chest pain, shortness of breath, rapid breathing or rapid heart rate

Health Tips for Abemaciclib

• Take Abemaciclib exactly as prescribed by doctor. Do not skip doses or stop taking them without consulting your doctor
• Eating a balanced diet, getting enough rest, and managing stress can support your body's ability
• Do not drive or use any machines if you experience dizziness, tiredness after taking Abemaciclib
• Avoid grapefruit or grapefruit juice or alcohol while you are taking the medicine as they may increase the concentration of Abemaciclib in the blood
• Drink an adequate amount of water daily to prevent dehydration
• Regular check-ups and follow-up appointments with your healthcare provider
• Inform your healthcare provider about any other medications you are using, including over-the-counter drugs and supplements
• Let your doctor know if you are pregnant or planning for pregnancy or breastfeeding women